TY - JOUR
T1 - A case of genital folliculosebaceous cystic hamartoma with an unique aggregated manifestation
AU - Hamada, Manabu
AU - Kiryu, Hiromaro
AU - Satoh, Emiko
AU - Moroi, Yoichi
AU - Urabe, Kazunori
AU - Furue, Masutaka
PY - 2006/3
Y1 - 2006/3
N2 - Folliculosebaceous cystic hamartoma (FCH) is a recently recognized cutaneous hamartoma composed of follicular, sebaceous and mesenchymal components, and usually occurring on the head and neck. We describe herein a case of FCH with an unique aggregated manifestation in a genital lesion. The patient was a 40-year-old woman with a genital lesion composed of a pedunculated nodule, a dome-shaped nodule and a subcutaneous nodule, measuring 5 cm in the greatest dimension. The largest, pedunculated nodule was histologically composed of an infundibulo-cystic structure with follicular, sebaceous and mesenchymal elements accompanied by cystic structures of various sizes lined by stratified squamous epithelium and follicular germinative cells suggesting follicular cysts. The dome-shaped nodule consisted of anastomosing strands of epithelial cells with follicular components. The subcutaneous nodule had two components, an infundibulo-cystic structure and a cyst lined by squamous epithelium. In our case, the unusual clinical feature of large and multiple nodules was due to the presence of several prominent hamartomatous cystic structures with FCH. This is the third case of giant FCH. The clinical presentation and location of giant FCH is unusual.
AB - Folliculosebaceous cystic hamartoma (FCH) is a recently recognized cutaneous hamartoma composed of follicular, sebaceous and mesenchymal components, and usually occurring on the head and neck. We describe herein a case of FCH with an unique aggregated manifestation in a genital lesion. The patient was a 40-year-old woman with a genital lesion composed of a pedunculated nodule, a dome-shaped nodule and a subcutaneous nodule, measuring 5 cm in the greatest dimension. The largest, pedunculated nodule was histologically composed of an infundibulo-cystic structure with follicular, sebaceous and mesenchymal elements accompanied by cystic structures of various sizes lined by stratified squamous epithelium and follicular germinative cells suggesting follicular cysts. The dome-shaped nodule consisted of anastomosing strands of epithelial cells with follicular components. The subcutaneous nodule had two components, an infundibulo-cystic structure and a cyst lined by squamous epithelium. In our case, the unusual clinical feature of large and multiple nodules was due to the presence of several prominent hamartomatous cystic structures with FCH. This is the third case of giant FCH. The clinical presentation and location of giant FCH is unusual.
UR - http://www.scopus.com/inward/record.url?scp=33645232387&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33645232387&partnerID=8YFLogxK
U2 - 10.1111/j.1346-8138.2006.00044.x
DO - 10.1111/j.1346-8138.2006.00044.x
M3 - Article
C2 - 16620225
AN - SCOPUS:33645232387
VL - 33
SP - 191
EP - 195
JO - Journal of Dermatology
JF - Journal of Dermatology
SN - 0385-2407
IS - 3
ER -