A case of interstitial pneumonia with smoldering adult T-cell leukemia

Saiko Ogata, Naoki Hamada, Takashige Maeyama, Koichi Takayama, Hiromasa Inoue, Yoichi Nakanishi

Research output: Contribution to journalArticle

Abstract

A 66-year-old woman was admitted because of dry cough and dyspnea. Computed tomography showed ground-glass opacities and traction bronchiectasis in both lung fields. Then, ATL cells appeared in her peripheral blood, and the number of lymphocytes in BALF increased. Inverse PCR for HTLV-1 clonality of the peripheral blood revealed a polyclonal pattern, and she was given a diagnosis of smoldering adult T-cell leukemia. Using BALF flow cytometry, both CD4- and CD25-positive cells accounted for only 0.8%. Secondary interstitial pneumonia was diagnosed and we started therapy with prednisolone and cyclophosphamide. BALF flow cytometry may be useful in the differential diagnosis of ATL lung lesions.

Original languageEnglish
Pages (from-to)293-297
Number of pages5
JournalNihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
Volume48
Issue number4
Publication statusPublished - Jan 1 2010

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Adult T Cell Leukemia Lymphoma
Interstitial Lung Diseases
Flow Cytometry
Lung
Human T-lymphotropic virus 1
Bronchiectasis
Lymphocyte Count
Traction
Prednisolone
Cough
Dyspnea
Cyclophosphamide
Glass
Differential Diagnosis
Tomography
Polymerase Chain Reaction
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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A case of interstitial pneumonia with smoldering adult T-cell leukemia. / Ogata, Saiko; Hamada, Naoki; Maeyama, Takashige; Takayama, Koichi; Inoue, Hiromasa; Nakanishi, Yoichi.

In: Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society, Vol. 48, No. 4, 01.01.2010, p. 293-297.

Research output: Contribution to journalArticle

Ogata, Saiko ; Hamada, Naoki ; Maeyama, Takashige ; Takayama, Koichi ; Inoue, Hiromasa ; Nakanishi, Yoichi. / A case of interstitial pneumonia with smoldering adult T-cell leukemia. In: Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society. 2010 ; Vol. 48, No. 4. pp. 293-297.
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