A case of liver metastasis of colon cancer demonstrating complete remission with combination chemotherapy of 5'-DFUR and MMC

Yoshihisa Sakaguchi; Akira Kabashima; Sosei Kuma; Kiyoshi Kajiyama

A case of liver metastasis of colon cancer demonstrating complete remission with combination chemotherapy of 5'-DFUR and MMC

Yoshihisa Sakaguchi, Akira Kabashima, Sosei Kuma, Kiyoshi Kajiyama

Faculty of Medical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

The patient was a 77-year-old man with advanced colon cancer and liver metastasis, who underwent right hemicolectomy and liver resection. After surgery, a new liver metastasis was found. Chemotherapy of 5'-deoxy-5-fluorouridine (5'-DFUR) and mitomycin C (MMC) was conducted for 6 months. 5'-DFUR was administered orally at 1,200 mg/day for 5 days/week in combination with intravenous administration of MMC at 10 mg/4-week. The treatment was effective and the lesion disappeared. The patient received a subsequent single administration of 5'-DFUR, and remained in remission for 3 years after surgery.

Original language	English
Pages (from-to)	875-878
Number of pages	4
Journal	Gan to kagaku ryoho. Cancer & chemotherapy
Volume	30
Issue number	6
Publication status	Published - Jun 2003

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

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title = "A case of liver metastasis of colon cancer demonstrating complete remission with combination chemotherapy of 5'-DFUR and MMC",

abstract = "The patient was a 77-year-old man with advanced colon cancer and liver metastasis, who underwent right hemicolectomy and liver resection. After surgery, a new liver metastasis was found. Chemotherapy of 5'-deoxy-5-fluorouridine (5'-DFUR) and mitomycin C (MMC) was conducted for 6 months. 5'-DFUR was administered orally at 1,200 mg/day for 5 days/week in combination with intravenous administration of MMC at 10 mg/4-week. The treatment was effective and the lesion disappeared. The patient received a subsequent single administration of 5'-DFUR, and remained in remission for 3 years after surgery.",

author = "Yoshihisa Sakaguchi and Akira Kabashima and Sosei Kuma and Kiyoshi Kajiyama",

year = "2003",

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language = "English",

volume = "30",

pages = "875--878",

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T1 - A case of liver metastasis of colon cancer demonstrating complete remission with combination chemotherapy of 5'-DFUR and MMC

AU - Sakaguchi, Yoshihisa

AU - Kabashima, Akira

AU - Kuma, Sosei

AU - Kajiyama, Kiyoshi

PY - 2003/6

Y1 - 2003/6

N2 - The patient was a 77-year-old man with advanced colon cancer and liver metastasis, who underwent right hemicolectomy and liver resection. After surgery, a new liver metastasis was found. Chemotherapy of 5'-deoxy-5-fluorouridine (5'-DFUR) and mitomycin C (MMC) was conducted for 6 months. 5'-DFUR was administered orally at 1,200 mg/day for 5 days/week in combination with intravenous administration of MMC at 10 mg/4-week. The treatment was effective and the lesion disappeared. The patient received a subsequent single administration of 5'-DFUR, and remained in remission for 3 years after surgery.

AB - The patient was a 77-year-old man with advanced colon cancer and liver metastasis, who underwent right hemicolectomy and liver resection. After surgery, a new liver metastasis was found. Chemotherapy of 5'-deoxy-5-fluorouridine (5'-DFUR) and mitomycin C (MMC) was conducted for 6 months. 5'-DFUR was administered orally at 1,200 mg/day for 5 days/week in combination with intravenous administration of MMC at 10 mg/4-week. The treatment was effective and the lesion disappeared. The patient received a subsequent single administration of 5'-DFUR, and remained in remission for 3 years after surgery.

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