A case of locally advanced sigmoid colon cancer curatively resected after neoadjuvant chemotherapy with FOLFIRI plus panitumumab

Kohei Horioka, Keizo Kaku, Sei Ichirou Jimi, Yoshihiro Oohata, Takafumi Kamei

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 72-year-old woman having abdominal pain and high fever was diagnosed with KRAS wild-type sigmoid colon cancer, invading the urinary bladder and uterus with a pelvic abscess. Considering the difficulty of curative resection, we first performed sigmoid colostomy and abscess drainage. Remarkable tumor regression was indicated by CT and colonoscopy after 1 course of FOLFIRI and 5 courses of FOLFIRI+panitumumab. Following an additional 2 courses of panitumumab, sigmoidectomy and partial cystectomy were performed. Six courses of FOLFIRI+panitumumab were administered postoperatively and no recurrence has been observed for 7 months. FOLFIRI+panitumumab may be an effective preoperative chemotherapy for patients with KRAS wild-type locally advanced colon cancer.

Original languageEnglish
Pages (from-to)397-399
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Volume40
Issue number3
Publication statusPublished - Mar 2013

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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