A case of mucosal cancer of the stomach treated by endoscopic submucosal dissection after which nodal metastasis became evident

Takashi Obana, Naotaka Fujita, Yutaka Noda, Dai Hirasawa, Kei Ito, Toshiki Sugawara, Yoshihiro Harada, Tetsuya Oohira, Hiroshi Honda, Takashi Sawai

Research output: Contribution to journalArticle

Abstract

An 82-year-old male was referred to our institution for evaluation and treatment of a protruding lesion in the stomach. Esophagogastroduodenoscopy (EGD) showed a small protruding lesion and a large superficial elevated lesion on the lesser curvature of the stomach (macroscopic type: 0-I and 0-IIa, resp.). CT and endoscopic ultrasonography (EUS) visualized a small round lymph node (LN) 11 mm in size near the lesser curvature, although submucosal invasion was not evident. These two lesions were resected en bloc by endoscopic submucosal dissection (ESD). Pathological examination of the resected specimen showed moderately differentiated tubular adenocarcinoma (tub2) and well-differentiated tubular adenocarcinoma (tub1), respectively, which were limited to the mucosal layer. Because lymphatic-vascular involvement was not detected by hematoxylin and eosin (HE) staining, additional gastrectomy was not performed. Two months after ESD, follow-up EUS and CT showed an enlarged LN. EUS-guided fine needle aspiration (EUS-FNA) for the LN revealed metastasis. Therefore, total gastrectomy with LN dissection was performed. His postoperative course was uneventful. After discharge, he has been followed up at the outpatient department without any sign of recurrence for 5 years. Histological reexamination of the ESD specimen using immunohistochemistry showed lymphatic invasion of cancer cells in the lamina propria of the 0-I lesion 13 mm in size.

Original languageEnglish
Article number853849
JournalCase Reports in Medicine
Volume2013
DOIs
Publication statusPublished - Jan 1 2013

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Endosonography
Stomach Neoplasms
Lymph Nodes
Gastrectomy
Neoplasm Metastasis
Stomach
Adenocarcinoma
Digestive System Endoscopy
Hematoxylin
Eosine Yellowish-(YS)
Fine Needle Biopsy
Lymph Node Excision
Blood Vessels
Mucous Membrane
Outpatients
Immunohistochemistry
Staining and Labeling
Recurrence
Endoscopic Mucosal Resection
Neoplasms

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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A case of mucosal cancer of the stomach treated by endoscopic submucosal dissection after which nodal metastasis became evident. / Obana, Takashi; Fujita, Naotaka; Noda, Yutaka; Hirasawa, Dai; Ito, Kei; Sugawara, Toshiki; Harada, Yoshihiro; Oohira, Tetsuya; Honda, Hiroshi; Sawai, Takashi.

In: Case Reports in Medicine, Vol. 2013, 853849, 01.01.2013.

Research output: Contribution to journalArticle

Obana, T, Fujita, N, Noda, Y, Hirasawa, D, Ito, K, Sugawara, T, Harada, Y, Oohira, T, Honda, H & Sawai, T 2013, 'A case of mucosal cancer of the stomach treated by endoscopic submucosal dissection after which nodal metastasis became evident', Case Reports in Medicine, vol. 2013, 853849. https://doi.org/10.1155/2013/853849
Obana, Takashi ; Fujita, Naotaka ; Noda, Yutaka ; Hirasawa, Dai ; Ito, Kei ; Sugawara, Toshiki ; Harada, Yoshihiro ; Oohira, Tetsuya ; Honda, Hiroshi ; Sawai, Takashi. / A case of mucosal cancer of the stomach treated by endoscopic submucosal dissection after which nodal metastasis became evident. In: Case Reports in Medicine. 2013 ; Vol. 2013.
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