A case of multiple gastric carcinoids associate with type a gastritis treated with antrectomy

Tomohiro Miyachi, Takashi Tsuchiya, Hiroshi Honda, Masaya Oikawa, Tetsuya Kakita, Atsushi Oyama, Ryuichiro Sato, Takashi Yazawa, Takahiro Tsuchiya, Kikuo Miyagawa

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Abstract

Type 1 gastric carcinoid is associated with Type A gastritis. A large amount of gastrin is secreted from antral G cells in response to achlorhydria in Type A gastritis. The hypergastrinemia has a trophic action on the enterochromaffin-like cells in the gastric fornix. This is a pathogenesis of Type 1 gastric carcinoid. We report a case of Type 1 gastric carcinoid treated by antrectomy. A 38-year-old man was found to have multiple polyps from the fornix to the upper gastric body with atrophic gastritis by gastroscopy. Polyp biopsy showed them to be carcinoid lesion. On laboratory examinations, hypergastrinemia and anti-parietal-cell antibodies were found. So they were diagnosed as Type 1 gastric carcinoid and anrectomy was done to suppress gastrin secretion. Postoperative serum gastrin concentration was normalized and gastric endoscopy showed complete regression of the carcinoid tumour.

Original languageEnglish
Pages (from-to)30-37
Number of pages8
JournalJapanese Journal of Gastroenterological Surgery
Volume45
Issue number1
DOIs
Publication statusPublished - Jan 21 2012

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All Science Journal Classification (ASJC) codes

  • Surgery
  • Gastroenterology

Cite this

Miyachi, T., Tsuchiya, T., Honda, H., Oikawa, M., Kakita, T., Oyama, A., ... Miyagawa, K. (2012). A case of multiple gastric carcinoids associate with type a gastritis treated with antrectomy. Japanese Journal of Gastroenterological Surgery, 45(1), 30-37. https://doi.org/10.5833/jjgs.45.30