A case of multiple gastric carcinoids associate with type a gastritis treated with antrectomy

Tomohiro Miyachi, Takashi Tsuchiya, Hiroshi Honda, Masaya Oikawa, Tetsuya Kakita, Atsushi Oyama, Ryuichiro Sato, Takashi Yazawa, Takahiro Tsuchiya, Kikuo Miyagawa

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Type 1 gastric carcinoid is associated with Type A gastritis. A large amount of gastrin is secreted from antral G cells in response to achlorhydria in Type A gastritis. The hypergastrinemia has a trophic action on the enterochromaffin-like cells in the gastric fornix. This is a pathogenesis of Type 1 gastric carcinoid. We report a case of Type 1 gastric carcinoid treated by antrectomy. A 38-year-old man was found to have multiple polyps from the fornix to the upper gastric body with atrophic gastritis by gastroscopy. Polyp biopsy showed them to be carcinoid lesion. On laboratory examinations, hypergastrinemia and anti-parietal-cell antibodies were found. So they were diagnosed as Type 1 gastric carcinoid and anrectomy was done to suppress gastrin secretion. Postoperative serum gastrin concentration was normalized and gastric endoscopy showed complete regression of the carcinoid tumour.

    Original languageEnglish
    Pages (from-to)30-37
    Number of pages8
    JournalJapanese Journal of Gastroenterological Surgery
    Volume45
    Issue number1
    DOIs
    Publication statusPublished - Jan 21 2012

    All Science Journal Classification (ASJC) codes

    • Surgery
    • Gastroenterology

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