A 44-year-old woman developed a malignant melanoma on the parietal region (pT4aN0M0, stage IIB). Two years later, another malignant melanoma had developed on her back (pT3bN1aM0, stage IIIB). Clinically, the second melanoma was a black hyperkeratotic nodule with crust formation, 16 × 12 mm in size, and did not fulfill the diagnostic criteria for epidermotropic metastatic malignant melanoma. Thus the second melanoma was also diagnosed as a primarylesion. Since the epidemiologyof multiple primarymelanoma in Japan has not been well evaluated due to its rarity, a careful follow-up is needed.
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