[A case of non-small cell lung cancer with hemodialysis which responded to docetaxel monotherapy].

Yumiko Abe, Kentaro Tanaka, Koichiro Matsumoto, Koichi Takayama, Hiroyuki Inoue, Miiru Izumi, Hiromasa Inoue, Yoichi Nakanishi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 56-year-old man receiving hemodialysis treatment was hospitalized for examination of a mass in the right middle lobe. Chest computed tomography showed a right hilar mass shadow accompanied by pleural effusion. Non-small cell lung cancer (NSCLC) was diagnosed by cytological examination of the pleural effusion. No epidermal growth factor receptor (EGFR) mutation was found. He was treated with 6 courses of docetaxel as first-line chemotherapy. Docetaxel was administered on the same day as hemodialysis. Adverse events, including hematotoxicity, were managed safely and no delay in administration occurred. This chemotherapy resulted in a partial response. Because docetaxel is metabolized in the liver and does not affect renal function, it can be administered as a standard regimen. This suggests that docetaxel monotherapy is an efficient therapy for non-small cell lung cancer patients receiving hemodialysis.

Original languageEnglish
Pages (from-to)769-773
Number of pages5
JournalNihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
Volume48
Issue number10
Publication statusPublished - Jan 1 2010

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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