A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer

Tomohiro Kitahara, Ichiro Takemasa, Akira Inoue, Hideki Osawa, Masaaki Miyo, Yukako Mokutani, Hisataka Ogawa, Atsushi Naito, Atsushi Hamabe, Masayuki Hiraki, Koji Munakata, Mamoru Uemura, Junichi Nishimura, Taishi Hata, Tsunekazu Mizushima, Hirofumi Yamamoto, Yuichiro Doki, Masaki Mori

Research output: Contribution to journalArticle

Abstract

A 70-year-old man presenting with melena was referred to our clinic. A clinical examination revealed a bulky tumor in the lower rectum. After ileostomy, 4 courses of capecitabine plus oxaliplatin (XELOX) therapy were administered as neoadjuvant chemotherapy. Computed tomography (CT) revealed significant reduction of the tumor. Laparoscopic super-low anterior resection with lateral lymph node dissection was performed. The pathological examination revealed no residual cancer cells, and a diagnosis of pathological complete response was made. The patient has been disease-free for 1 year after the operation. Neoadjuvant chemotherapy with XELOX might be promising for patients with locally advanced rectal cancer.

Original languageEnglish
Pages (from-to)1569-1571
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Volume41
Issue number12
Publication statusPublished - Nov 1 2014
Externally publishedYes

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oxaliplatin
Rectal Neoplasms
Melena
Drug Therapy
Ileostomy
Residual Neoplasm
Lymph Node Excision
Rectum
Neoplasms
Tomography
XELOX
Therapeutics
Capecitabine

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer. / Kitahara, Tomohiro; Takemasa, Ichiro; Inoue, Akira; Osawa, Hideki; Miyo, Masaaki; Mokutani, Yukako; Ogawa, Hisataka; Naito, Atsushi; Hamabe, Atsushi; Hiraki, Masayuki; Munakata, Koji; Uemura, Mamoru; Nishimura, Junichi; Hata, Taishi; Mizushima, Tsunekazu; Yamamoto, Hirofumi; Doki, Yuichiro; Mori, Masaki.

In: Japanese Journal of Cancer and Chemotherapy, Vol. 41, No. 12, 01.11.2014, p. 1569-1571.

Research output: Contribution to journalArticle

Kitahara, T, Takemasa, I, Inoue, A, Osawa, H, Miyo, M, Mokutani, Y, Ogawa, H, Naito, A, Hamabe, A, Hiraki, M, Munakata, K, Uemura, M, Nishimura, J, Hata, T, Mizushima, T, Yamamoto, H, Doki, Y & Mori, M 2014, 'A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer', Japanese Journal of Cancer and Chemotherapy, vol. 41, no. 12, pp. 1569-1571.
Kitahara, Tomohiro ; Takemasa, Ichiro ; Inoue, Akira ; Osawa, Hideki ; Miyo, Masaaki ; Mokutani, Yukako ; Ogawa, Hisataka ; Naito, Atsushi ; Hamabe, Atsushi ; Hiraki, Masayuki ; Munakata, Koji ; Uemura, Mamoru ; Nishimura, Junichi ; Hata, Taishi ; Mizushima, Tsunekazu ; Yamamoto, Hirofumi ; Doki, Yuichiro ; Mori, Masaki. / A case of pathological complete response with neoadjuvant XELOX chemotherapy for locally advanced rectal cancer. In: Japanese Journal of Cancer and Chemotherapy. 2014 ; Vol. 41, No. 12. pp. 1569-1571.
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