A case of perianal Bowen's disease successfully treated with 5% topical imiquimod

Miki Uryu, Yoko Kuba, Akiko Satomura, Chikage Mitoma, Masakazu Takahara, Yoichi Moroi, Masutaka Furue

Research output: Contribution to journalArticle


We report a case of perianal Bowen's disease in a 61-year-old woman with a complete response to 5% topical imiquimod. She presented with a brownish plaque in the perianal area. A biopsied specimen showed epidermal hyperkeratosis, acanthosis, proliferation of atypical keratinocytes, abnormal mitosis and multinucleated cells, which led to the diagnosis of Bowen's disease. The lesion completely disappeared after application of 5% topical imiquimod three times a week for 8 weeks. No relapse was observed either clinically or histologically three months after the treatment.

Original languageEnglish
Pages (from-to)149-152
Number of pages4
JournalNishinihon Journal of Dermatology
Issue number2
Publication statusPublished - Dec 27 2012


All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this