TY - JOUR
T1 - A case of perianal Bowen's disease successfully treated with 5% topical imiquimod
AU - Uryu, Miki
AU - Kuba, Yoko
AU - Satomura, Akiko
AU - Mitoma, Chikage
AU - Takahara, Masakazu
AU - Moroi, Yoichi
AU - Furue, Masutaka
PY - 2012
Y1 - 2012
N2 - We report a case of perianal Bowen's disease in a 61-year-old woman with a complete response to 5% topical imiquimod. She presented with a brownish plaque in the perianal area. A biopsied specimen showed epidermal hyperkeratosis, acanthosis, proliferation of atypical keratinocytes, abnormal mitosis and multinucleated cells, which led to the diagnosis of Bowen's disease. The lesion completely disappeared after application of 5% topical imiquimod three times a week for 8 weeks. No relapse was observed either clinically or histologically three months after the treatment.
AB - We report a case of perianal Bowen's disease in a 61-year-old woman with a complete response to 5% topical imiquimod. She presented with a brownish plaque in the perianal area. A biopsied specimen showed epidermal hyperkeratosis, acanthosis, proliferation of atypical keratinocytes, abnormal mitosis and multinucleated cells, which led to the diagnosis of Bowen's disease. The lesion completely disappeared after application of 5% topical imiquimod three times a week for 8 weeks. No relapse was observed either clinically or histologically three months after the treatment.
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U2 - 10.2336/nishinihonhifu.74.149
DO - 10.2336/nishinihonhifu.74.149
M3 - Article
AN - SCOPUS:84871418603
SN - 0386-9784
VL - 74
SP - 149
EP - 152
JO - Nishinihon Journal of Dermatology
JF - Nishinihon Journal of Dermatology
IS - 2
ER -