TY - JOUR
T1 - A Case of Primary Cutaneous B-cell Lymphoma
AU - Murakami, Yoshiyuki
AU - Urabe, Kazunori
AU - Furue, Masutaka
AU - Irie, Koji
PY - 1998/1/1
Y1 - 1998/1/1
N2 - We herein report the ease of a 75-year-old Japanese woman who presented with multiple cutaneous nodules on her trunk and left upper limb and thus was diagnosed to have primary cutaneous B-cell lymphoma (pCBCL). We could not detect any extra-cutaneous lesions in the patient. Histologically, the nodule showed nonepidermotropic diffuse dermal infiltrates, which mainly consisted of large abnormal lymphoid cells. Imrnunohistochernically, these neoplastic cells expressed CD19, CD20, x type slg. An immunoglobulin gene rearrangement of the neoplastic cells of the cutaneous nodule was shown by a Southern blot analysis. Based on these clinical and laboratory findings, she was diagnosed to have diffuse large cell type pCBCL. She was treated by THP-COP chemotherapy and 30 Gy of local radiotherapy with an electron beam. No relapse was noticed at 14 months after the initial treatment.
AB - We herein report the ease of a 75-year-old Japanese woman who presented with multiple cutaneous nodules on her trunk and left upper limb and thus was diagnosed to have primary cutaneous B-cell lymphoma (pCBCL). We could not detect any extra-cutaneous lesions in the patient. Histologically, the nodule showed nonepidermotropic diffuse dermal infiltrates, which mainly consisted of large abnormal lymphoid cells. Imrnunohistochernically, these neoplastic cells expressed CD19, CD20, x type slg. An immunoglobulin gene rearrangement of the neoplastic cells of the cutaneous nodule was shown by a Southern blot analysis. Based on these clinical and laboratory findings, she was diagnosed to have diffuse large cell type pCBCL. She was treated by THP-COP chemotherapy and 30 Gy of local radiotherapy with an electron beam. No relapse was noticed at 14 months after the initial treatment.
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U2 - 10.2336/nishinihonhifu.60.471
DO - 10.2336/nishinihonhifu.60.471
M3 - Article
AN - SCOPUS:85024736595
VL - 60
SP - 471
EP - 475
JO - Nishinihon Journal of Dermatology
JF - Nishinihon Journal of Dermatology
SN - 0386-9784
IS - 4
ER -