TY - JOUR
T1 - A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease
AU - Kakigao, Kana
AU - Fukushima, Nobuyoshi
AU - Mizutani, Takahiro
AU - Haraguchi, Kazuhiro
AU - Okamoto, Risa
AU - Sawamura, Noriko
AU - Oohashi, Tomoko
AU - Mitsuyasu, Aya
AU - Fujiyama, Takashi
AU - Yoshimoto, Tsuyoshi
AU - Koujima, Motoyuki
AU - Kawabe, Ken
AU - Fukuizumi, Kunitaka
AU - Nakamuta, Makoto
AU - Harada, Naohiko
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2012/10
Y1 - 2012/10
N2 - Case reports of protein-losing gastroenteropathy (PLGE) associated with not only mixed connective tissue disease (MCTD) but also Sjögren syndrome (SjS) are very rare. We report a first case of PLGE in a patient with both MCTD and SjS. A 58-year-old Japanese woman was referred and admitted to our hospital because of abdominal fullness and lower leg edema Her past medical history revealed SjS at age 40. Physical examination demonstrated lower leg edema and Raynaud's phenomenon. Blood chemistry data showed severe hypoproteinemia. Anti RNP antibody was positive. MCTD was diagnosed. The alpha-1 antitrypsin clearance level was high. The 99mTc-DTPA human serum albumin scintigraphy demonstrated abnormal accumulation in the intestine. PLGE associated with both MCTD and SjS was diagnosed, but she was successfully treated by prednisolone.
AB - Case reports of protein-losing gastroenteropathy (PLGE) associated with not only mixed connective tissue disease (MCTD) but also Sjögren syndrome (SjS) are very rare. We report a first case of PLGE in a patient with both MCTD and SjS. A 58-year-old Japanese woman was referred and admitted to our hospital because of abdominal fullness and lower leg edema Her past medical history revealed SjS at age 40. Physical examination demonstrated lower leg edema and Raynaud's phenomenon. Blood chemistry data showed severe hypoproteinemia. Anti RNP antibody was positive. MCTD was diagnosed. The alpha-1 antitrypsin clearance level was high. The 99mTc-DTPA human serum albumin scintigraphy demonstrated abnormal accumulation in the intestine. PLGE associated with both MCTD and SjS was diagnosed, but she was successfully treated by prednisolone.
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M3 - Article
C2 - 23047635
AN - SCOPUS:84868561176
VL - 109
SP - 1770
EP - 1775
JO - Japanese Journal of Gastroenterology
JF - Japanese Journal of Gastroenterology
SN - 0446-6586
IS - 10
ER -