A case of pulmonary hypertension associated with systemic lupus erythematosus without anti-ribonucleoprotein antibodies

Eiji Suzuki, Taichi Hayashi, Satoshi Ito, Kunihiko Miyazaki, Hiroshi Yamazaki, Takeshi Machino, Reiko Takahashi, Yusuke Chino, Daisuke Goto, Isao Matsumoto, Akito Tsutsumi, Yukio Sato, Takayuki Sumida

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Abstract

We encountered a 32-year-old woman presenting with high-grade fever and swollen lymph nodes. Echocardiography showed a pericardial effusion and progressive pulmonary hypertension (PH). Although the criteria for systemic lupus erythematosus (SLE) were met, typical laboratory values and symptoms of SLE were not present. Anti-ribonucleaoprotein antibodies were negative. Computed tomography (CT) showed a dilatation of peripheral arteries and veins and a thickening of the interlobular septa. The patient was given anti-coagulants, but these were not effective. Steroids, however, improved her condition dramatically. The clinical course of this patient indicates the importance of steroid therapy for PH even when the patient does not show the typical clinical features of SLE.

Original languageEnglish
Pages (from-to)87-93
Number of pages7
JournalActa Medica et Biologica
Volume53
Issue number3
Publication statusPublished - Sep 1 2005

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All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Suzuki, E., Hayashi, T., Ito, S., Miyazaki, K., Yamazaki, H., Machino, T., ... Sumida, T. (2005). A case of pulmonary hypertension associated with systemic lupus erythematosus without anti-ribonucleoprotein antibodies. Acta Medica et Biologica, 53(3), 87-93.