A case of recurrent sigmoid colon cancer with adrenal and para-aortic lymph node metastasis successfully treated by operation and chemotherapy

Ho Min Kim, Masataka Ikeda, Miho Okano, Norikatsu Miyoshi, Hajime Hirose, Shinya Yamashita, Ichiro Takemasa, Tsunekazu Mizushima, Hirofumi Yamamoto, Mitsugu Sekimoto, Yuichiro Dokl, Masaki Mori

Research output: Contribution to journalArticle

Abstract

We report a case of 57-year-old woman suffering from advanced sigmoid colon cancer with adrenal and para-aortic lymph node recurrence. Sigmoidectomy was performed for sigmoid colon cancer in January 2002. Pathological staging was Stage II (pT3, pNO, pMO, Cur A). She received a UFT + CPT-11 regimen as preoperative chemotherapy for liver metastasis (S2, S7) from December 2002. A partial liver resection (S2, S7) was performed for liver metastasis in July 2003, and the UFT+CPT-11 was introduced as adjuvant chemotherapy. However, adrenal and para-aortic lymph node recurrence was detected in February 2007, and mFOLFOX6 was performed as preoperative chemotherapy. Right adrenalectomy and para-aortic lymph node dissection was performed in July 2007. mFOLFOX6 as postoperative chemotherapy was done, mFOLFOX6 + bevacizumab was started because of CEA increase. The chemotherapy was performed for 23 courses and temporarily stopped due to adverse reactions, such as peripheral neuropathy (grade 2), general fatigue (grade 1), and nausea (grade 1). She had no recurrence for almost 3 years after a resection of adrenal and para-aortic lymph node metastasis.

Original languageEnglish
Pages (from-to)2548-2550
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Volume37
Issue number12
Publication statusPublished - Jan 1 2010
Externally publishedYes

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Sigmoid Neoplasms
irinotecan
Lymph Nodes
ethyl-2-methylthio-4-methyl-5-pyrimidine carboxylate
Neoplasm Metastasis
Drug Therapy
Recurrence
Liver
Adrenalectomy
Peripheral Nervous System Diseases
Adjuvant Chemotherapy
Lymph Node Excision
Nausea
Fatigue

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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A case of recurrent sigmoid colon cancer with adrenal and para-aortic lymph node metastasis successfully treated by operation and chemotherapy. / Kim, Ho Min; Ikeda, Masataka; Okano, Miho; Miyoshi, Norikatsu; Hirose, Hajime; Yamashita, Shinya; Takemasa, Ichiro; Mizushima, Tsunekazu; Yamamoto, Hirofumi; Sekimoto, Mitsugu; Dokl, Yuichiro; Mori, Masaki.

In: Japanese Journal of Cancer and Chemotherapy, Vol. 37, No. 12, 01.01.2010, p. 2548-2550.

Research output: Contribution to journalArticle

Kim, HM, Ikeda, M, Okano, M, Miyoshi, N, Hirose, H, Yamashita, S, Takemasa, I, Mizushima, T, Yamamoto, H, Sekimoto, M, Dokl, Y & Mori, M 2010, 'A case of recurrent sigmoid colon cancer with adrenal and para-aortic lymph node metastasis successfully treated by operation and chemotherapy', Japanese Journal of Cancer and Chemotherapy, vol. 37, no. 12, pp. 2548-2550.
Kim, Ho Min ; Ikeda, Masataka ; Okano, Miho ; Miyoshi, Norikatsu ; Hirose, Hajime ; Yamashita, Shinya ; Takemasa, Ichiro ; Mizushima, Tsunekazu ; Yamamoto, Hirofumi ; Sekimoto, Mitsugu ; Dokl, Yuichiro ; Mori, Masaki. / A case of recurrent sigmoid colon cancer with adrenal and para-aortic lymph node metastasis successfully treated by operation and chemotherapy. In: Japanese Journal of Cancer and Chemotherapy. 2010 ; Vol. 37, No. 12. pp. 2548-2550.
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