A case of repeated surgical resections for tumor seeding of hepatocellular carcinoma after radiof requency ablation

Yasunari Fukuda, Tadafumi Asaoka, Hidetoshi Eguchi, Yoshifumi Iwagami, Daisaku Yamada, Takehiro Noda, Koichi Kawamoto, Kunihito Gotoh, Shogo Kobayashi, Yuichiro Doki, Masaki Mori

Research output: Contribution to journalReview article

Abstract

We report a case of repeated surgical resections for the tumor seeding of hepatocellular carcinoma (HCO after radiofrequency ablation (RFA). A 79-year-old man, who had an intrahepatic recurrence of HCC (segment 2) 5 months after RFA, was referred to our hospital for surgery, and underwent a laparoscopic lateral segmentectomy. Histological examination showed a poorly differentiated HCC (pStage II). Eight months after RFA, subcutaneous nodules along the RFA needle tract were pointed out by abdominal CT, and a tumorectomy was performed. Nineteen months after RFA, abdominal CT showed a 33 mm tumor on the side of the spleen, leading to the diagnosis of the peritoneal dissemination following RFA. The tumor has been growing up to 49 mm in size in spite of a radiation therapy. Accordingly, a laparoscopic tumorectomy was performed 26 months after RFA. His resected tumors were morphologically identical to the intrahepatic recurrence of HCC. The patient had remained recurrence-free for 4 months after the second tumorectomy. Our case demonstrated the utility of surgical resection for the tumor seeding of HCC following RFA.

Original languageEnglish
Pages (from-to)342-344
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Volume45
Issue number2
Publication statusPublished - Feb 1 2018
Externally publishedYes

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Hepatocellular Carcinoma
Neoplasms
Recurrence
Segmental Mastectomy
Needles
Radiotherapy
Spleen

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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A case of repeated surgical resections for tumor seeding of hepatocellular carcinoma after radiof requency ablation. / Fukuda, Yasunari; Asaoka, Tadafumi; Eguchi, Hidetoshi; Iwagami, Yoshifumi; Yamada, Daisaku; Noda, Takehiro; Kawamoto, Koichi; Gotoh, Kunihito; Kobayashi, Shogo; Doki, Yuichiro; Mori, Masaki.

In: Japanese Journal of Cancer and Chemotherapy, Vol. 45, No. 2, 01.02.2018, p. 342-344.

Research output: Contribution to journalReview article

Fukuda, Y, Asaoka, T, Eguchi, H, Iwagami, Y, Yamada, D, Noda, T, Kawamoto, K, Gotoh, K, Kobayashi, S, Doki, Y & Mori, M 2018, 'A case of repeated surgical resections for tumor seeding of hepatocellular carcinoma after radiof requency ablation', Japanese Journal of Cancer and Chemotherapy, vol. 45, no. 2, pp. 342-344.
Fukuda, Yasunari ; Asaoka, Tadafumi ; Eguchi, Hidetoshi ; Iwagami, Yoshifumi ; Yamada, Daisaku ; Noda, Takehiro ; Kawamoto, Koichi ; Gotoh, Kunihito ; Kobayashi, Shogo ; Doki, Yuichiro ; Mori, Masaki. / A case of repeated surgical resections for tumor seeding of hepatocellular carcinoma after radiof requency ablation. In: Japanese Journal of Cancer and Chemotherapy. 2018 ; Vol. 45, No. 2. pp. 342-344.
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AU - Iwagami, Yoshifumi

AU - Yamada, Daisaku

AU - Noda, Takehiro

AU - Kawamoto, Koichi

AU - Gotoh, Kunihito

AU - Kobayashi, Shogo

AU - Doki, Yuichiro

AU - Mori, Masaki

PY - 2018/2/1

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N2 - We report a case of repeated surgical resections for the tumor seeding of hepatocellular carcinoma (HCO after radiofrequency ablation (RFA). A 79-year-old man, who had an intrahepatic recurrence of HCC (segment 2) 5 months after RFA, was referred to our hospital for surgery, and underwent a laparoscopic lateral segmentectomy. Histological examination showed a poorly differentiated HCC (pStage II). Eight months after RFA, subcutaneous nodules along the RFA needle tract were pointed out by abdominal CT, and a tumorectomy was performed. Nineteen months after RFA, abdominal CT showed a 33 mm tumor on the side of the spleen, leading to the diagnosis of the peritoneal dissemination following RFA. The tumor has been growing up to 49 mm in size in spite of a radiation therapy. Accordingly, a laparoscopic tumorectomy was performed 26 months after RFA. His resected tumors were morphologically identical to the intrahepatic recurrence of HCC. The patient had remained recurrence-free for 4 months after the second tumorectomy. Our case demonstrated the utility of surgical resection for the tumor seeding of HCC following RFA.

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