A case of retinoblastoma with marked infiltration in the optic nerve

Minako Ushijima, Hiroshi Yoshikawa, Yoko Onishi, Tatsuro Ishibashi, Aiko Suminoe, Ynhki Koga, Kaori Asai, Yoshiyuki Shioyama

Research output: Contribution to journalArticle

Abstract

Purpose: To report retinoblastoma with marked involvement of the optic nerve in an infant. Case: A 19-month-old male infant presented with opaque cornea in the left eye. Abnormal eye position had been present since one year before. Family members showed no notable events. Findings: The left eye was directed outwards with rubeosis iridis and corneal diameter of 13 mm. Echography showed tumor mass with calcification. The left optic nerve showed swelling anterior to the orbital apex. The left eye was enucleated after two courses of systemic and intrathecal chemotherapy. The optic nerve was dissected 15 mm posterior to the eyeglobe. The patient received further systemic and intrathecal chemotherapy with irradiation of the optic nerve anterior to the chiasm. He has been doing well for 34 months until present. Conclusion: Systemic and intrathecal chemotherapy followed by enucleation was effective for retinoblastoma with marked involvement of the optic nerve in an infant.

Original languageEnglish
Pages (from-to)661-664
Number of pages4
JournalJapanese Journal of Clinical Ophthalmology
Volume68
Issue number5
Publication statusPublished - May 2014

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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