A case of sarcoidosis, diagnosed from conjunctival tumor

Ichiro Ueno; Hiroshi Yoshikawa; Ri Ichiro Kohno; Tatsuro Ishibashi; Ken Ichi Ueno

A case of sarcoidosis, diagnosed from conjunctival tumor

Ichiro Ueno, Hiroshi Yoshikawa, Ri Ichiro Kohno, Tatsuro Ishibashi, Ken Ichi Ueno

Kyushu University Hospital

Research output: Contribution to journal › Article › peer-review

Abstract

Background: We present a rare case of sarcoidosis presenting with symptoms of conjunctival mass. Case Report: A 71-year-old female complained of dry-eye sensation. A nodular tumor about 15×3 mm was found in the lower fornix of each conjunctiva. Histopathologic examination showed that the tumors were sarcoid granulomas. No intraocular lesions were detected. Laboratory studies showed elevated levels of serum angiotensin-converting enzyme and lysozyme. Computed tomography showed remarkable enlargement of mediastinal lymph nodes. Bronchoalveolar lavage fluid showed an elevated CD4/CD8 ratio. Mantoux test results were negative for tuberculosis. Three months later, "snowball" vitreous opacity appeared and inflammatory cells were found in the anterior chamber, and we administered a sub-Tenon's injection of triamcinolone acetonide. Conclusion: Ophthalmologists should consider sarcoidosis in the differential diagnosis of conjunctival masses.

Original language	English
Pages (from-to)	274-277
Number of pages	4
Journal	Folia Ophthalmologica Japonica
Volume	56
Issue number	4
Publication status	Published - Apr 2005

All Science Journal Classification (ASJC) codes

Ophthalmology

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title = "A case of sarcoidosis, diagnosed from conjunctival tumor",

abstract = "Background: We present a rare case of sarcoidosis presenting with symptoms of conjunctival mass. Case Report: A 71-year-old female complained of dry-eye sensation. A nodular tumor about 15×3 mm was found in the lower fornix of each conjunctiva. Histopathologic examination showed that the tumors were sarcoid granulomas. No intraocular lesions were detected. Laboratory studies showed elevated levels of serum angiotensin-converting enzyme and lysozyme. Computed tomography showed remarkable enlargement of mediastinal lymph nodes. Bronchoalveolar lavage fluid showed an elevated CD4/CD8 ratio. Mantoux test results were negative for tuberculosis. Three months later, {"}snowball{"} vitreous opacity appeared and inflammatory cells were found in the anterior chamber, and we administered a sub-Tenon's injection of triamcinolone acetonide. Conclusion: Ophthalmologists should consider sarcoidosis in the differential diagnosis of conjunctival masses.",

author = "Ichiro Ueno and Hiroshi Yoshikawa and Kohno, {Ri Ichiro} and Tatsuro Ishibashi and Ueno, {Ken Ichi}",

year = "2005",

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language = "English",

volume = "56",

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journal = "Folia Ophthalmologica Japonica",

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T1 - A case of sarcoidosis, diagnosed from conjunctival tumor

AU - Ueno, Ichiro

AU - Yoshikawa, Hiroshi

AU - Kohno, Ri Ichiro

AU - Ishibashi, Tatsuro

AU - Ueno, Ken Ichi

PY - 2005/4

Y1 - 2005/4

N2 - Background: We present a rare case of sarcoidosis presenting with symptoms of conjunctival mass. Case Report: A 71-year-old female complained of dry-eye sensation. A nodular tumor about 15×3 mm was found in the lower fornix of each conjunctiva. Histopathologic examination showed that the tumors were sarcoid granulomas. No intraocular lesions were detected. Laboratory studies showed elevated levels of serum angiotensin-converting enzyme and lysozyme. Computed tomography showed remarkable enlargement of mediastinal lymph nodes. Bronchoalveolar lavage fluid showed an elevated CD4/CD8 ratio. Mantoux test results were negative for tuberculosis. Three months later, "snowball" vitreous opacity appeared and inflammatory cells were found in the anterior chamber, and we administered a sub-Tenon's injection of triamcinolone acetonide. Conclusion: Ophthalmologists should consider sarcoidosis in the differential diagnosis of conjunctival masses.

AB - Background: We present a rare case of sarcoidosis presenting with symptoms of conjunctival mass. Case Report: A 71-year-old female complained of dry-eye sensation. A nodular tumor about 15×3 mm was found in the lower fornix of each conjunctiva. Histopathologic examination showed that the tumors were sarcoid granulomas. No intraocular lesions were detected. Laboratory studies showed elevated levels of serum angiotensin-converting enzyme and lysozyme. Computed tomography showed remarkable enlargement of mediastinal lymph nodes. Bronchoalveolar lavage fluid showed an elevated CD4/CD8 ratio. Mantoux test results were negative for tuberculosis. Three months later, "snowball" vitreous opacity appeared and inflammatory cells were found in the anterior chamber, and we administered a sub-Tenon's injection of triamcinolone acetonide. Conclusion: Ophthalmologists should consider sarcoidosis in the differential diagnosis of conjunctival masses.

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