A case of scirrhous gastric carcinoma with peritoneal dissemination which was treated by curative gastrectomy after S-1/CDDP chemotherapy

Tomonori Akagi, Tsuyoshi Etoh, Hidetoshi Eguchi, Kazuaki Hiroishi, Yoshitake Ueda, Kazuhiro Yasuda, Tsuyoshi Noguchi, Norio Shiraishi, Seigo Kitano

Research output: Contribution to journalArticle

Abstract

The present patient was a 53-year-old female diagnosed as gastric cancer with peritoneal dissemination by staging laparoscopy. She was treated with chemotherapy using S-1 (80 mg/body/day) and CDDP (80 mg/body/day, day 8) administered for 3 weeks followed by a drug-free 2 weeks, in five-week courses. Stable disease (SD) was obtained after six courses, and then she underwent second-staging laparoscopy. Because of disappearing peritoneal disseminated nodules both macroscopically and histologically, she underwent curative total gastrectomy with D2 lymph node dissection and reconstruction by the Roux-en Y method. The postoperative pathological findings showed T2 (se) N1M0, stage IIIa and chemotherapy effective evaluation demonstrated Grade 1b. Postoperatively, S-1/CDDP therapy was carried out, after two cycles she suffered from anorexia, and then S-1 only was given. Fourteen months later, peritoneal dissemination developed. Despite changes in the regimen such as docetaxel or CPT-11, she died 23 months after the initial gastrectomy.

Original languageEnglish
Pages (from-to)1573-1577
Number of pages5
JournalJapanese Journal of Cancer and Chemotherapy
Volume37
Issue number8
Publication statusPublished - Aug 15 2010

Fingerprint

Scirrhous Adenocarcinoma
irinotecan
docetaxel
Gastrectomy
Laparoscopy
Stomach
Drug Therapy
Anorexia
Lymph Node Excision
Stomach Neoplasms
Pharmaceutical Preparations
Therapeutics

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

A case of scirrhous gastric carcinoma with peritoneal dissemination which was treated by curative gastrectomy after S-1/CDDP chemotherapy. / Akagi, Tomonori; Etoh, Tsuyoshi; Eguchi, Hidetoshi; Hiroishi, Kazuaki; Ueda, Yoshitake; Yasuda, Kazuhiro; Noguchi, Tsuyoshi; Shiraishi, Norio; Kitano, Seigo.

In: Japanese Journal of Cancer and Chemotherapy, Vol. 37, No. 8, 15.08.2010, p. 1573-1577.

Research output: Contribution to journalArticle

Akagi, T, Etoh, T, Eguchi, H, Hiroishi, K, Ueda, Y, Yasuda, K, Noguchi, T, Shiraishi, N & Kitano, S 2010, 'A case of scirrhous gastric carcinoma with peritoneal dissemination which was treated by curative gastrectomy after S-1/CDDP chemotherapy', Japanese Journal of Cancer and Chemotherapy, vol. 37, no. 8, pp. 1573-1577.
Akagi, Tomonori ; Etoh, Tsuyoshi ; Eguchi, Hidetoshi ; Hiroishi, Kazuaki ; Ueda, Yoshitake ; Yasuda, Kazuhiro ; Noguchi, Tsuyoshi ; Shiraishi, Norio ; Kitano, Seigo. / A case of scirrhous gastric carcinoma with peritoneal dissemination which was treated by curative gastrectomy after S-1/CDDP chemotherapy. In: Japanese Journal of Cancer and Chemotherapy. 2010 ; Vol. 37, No. 8. pp. 1573-1577.
@article{edfab8fbc17d4d77b69d252e9f6f033b,
title = "A case of scirrhous gastric carcinoma with peritoneal dissemination which was treated by curative gastrectomy after S-1/CDDP chemotherapy",
abstract = "The present patient was a 53-year-old female diagnosed as gastric cancer with peritoneal dissemination by staging laparoscopy. She was treated with chemotherapy using S-1 (80 mg/body/day) and CDDP (80 mg/body/day, day 8) administered for 3 weeks followed by a drug-free 2 weeks, in five-week courses. Stable disease (SD) was obtained after six courses, and then she underwent second-staging laparoscopy. Because of disappearing peritoneal disseminated nodules both macroscopically and histologically, she underwent curative total gastrectomy with D2 lymph node dissection and reconstruction by the Roux-en Y method. The postoperative pathological findings showed T2 (se) N1M0, stage IIIa and chemotherapy effective evaluation demonstrated Grade 1b. Postoperatively, S-1/CDDP therapy was carried out, after two cycles she suffered from anorexia, and then S-1 only was given. Fourteen months later, peritoneal dissemination developed. Despite changes in the regimen such as docetaxel or CPT-11, she died 23 months after the initial gastrectomy.",
author = "Tomonori Akagi and Tsuyoshi Etoh and Hidetoshi Eguchi and Kazuaki Hiroishi and Yoshitake Ueda and Kazuhiro Yasuda and Tsuyoshi Noguchi and Norio Shiraishi and Seigo Kitano",
year = "2010",
month = "8",
day = "15",
language = "English",
volume = "37",
pages = "1573--1577",
journal = "Japanese Journal of Cancer and Chemotherapy",
issn = "0385-0684",
publisher = "Japanese Journal of Cancer and Chemotherapy Publishers Inc.",
number = "8",

}

TY - JOUR

T1 - A case of scirrhous gastric carcinoma with peritoneal dissemination which was treated by curative gastrectomy after S-1/CDDP chemotherapy

AU - Akagi, Tomonori

AU - Etoh, Tsuyoshi

AU - Eguchi, Hidetoshi

AU - Hiroishi, Kazuaki

AU - Ueda, Yoshitake

AU - Yasuda, Kazuhiro

AU - Noguchi, Tsuyoshi

AU - Shiraishi, Norio

AU - Kitano, Seigo

PY - 2010/8/15

Y1 - 2010/8/15

N2 - The present patient was a 53-year-old female diagnosed as gastric cancer with peritoneal dissemination by staging laparoscopy. She was treated with chemotherapy using S-1 (80 mg/body/day) and CDDP (80 mg/body/day, day 8) administered for 3 weeks followed by a drug-free 2 weeks, in five-week courses. Stable disease (SD) was obtained after six courses, and then she underwent second-staging laparoscopy. Because of disappearing peritoneal disseminated nodules both macroscopically and histologically, she underwent curative total gastrectomy with D2 lymph node dissection and reconstruction by the Roux-en Y method. The postoperative pathological findings showed T2 (se) N1M0, stage IIIa and chemotherapy effective evaluation demonstrated Grade 1b. Postoperatively, S-1/CDDP therapy was carried out, after two cycles she suffered from anorexia, and then S-1 only was given. Fourteen months later, peritoneal dissemination developed. Despite changes in the regimen such as docetaxel or CPT-11, she died 23 months after the initial gastrectomy.

AB - The present patient was a 53-year-old female diagnosed as gastric cancer with peritoneal dissemination by staging laparoscopy. She was treated with chemotherapy using S-1 (80 mg/body/day) and CDDP (80 mg/body/day, day 8) administered for 3 weeks followed by a drug-free 2 weeks, in five-week courses. Stable disease (SD) was obtained after six courses, and then she underwent second-staging laparoscopy. Because of disappearing peritoneal disseminated nodules both macroscopically and histologically, she underwent curative total gastrectomy with D2 lymph node dissection and reconstruction by the Roux-en Y method. The postoperative pathological findings showed T2 (se) N1M0, stage IIIa and chemotherapy effective evaluation demonstrated Grade 1b. Postoperatively, S-1/CDDP therapy was carried out, after two cycles she suffered from anorexia, and then S-1 only was given. Fourteen months later, peritoneal dissemination developed. Despite changes in the regimen such as docetaxel or CPT-11, she died 23 months after the initial gastrectomy.

UR - http://www.scopus.com/inward/record.url?scp=79961107643&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79961107643&partnerID=8YFLogxK

M3 - Article

C2 - 20716890

AN - SCOPUS:79961107643

VL - 37

SP - 1573

EP - 1577

JO - Japanese Journal of Cancer and Chemotherapy

JF - Japanese Journal of Cancer and Chemotherapy

SN - 0385-0684

IS - 8

ER -