A case of secondary hemochromatosis with elevated serum interleukin-6

Midori Tsutsumi, Misa Nakamura, Sotaro Kawazu, Takamichi Ito, Masutaka Furue

Research output: Contribution to journalArticle

Abstract

Here we report a case of an 88-year-old woman with secondary hemochromatosis. Because of severe anemia, she had received blood transfusions many times in the past three years. She had a history of surgical treatments for uterine cervical cancer and rectal cancer. Her entire skin showed a progressive greyish-blue hue. Histopathologically, Berlin blue staining-positive granules were found in the dermis and the subcutaneous tissue. Ultrasound sonography, CT, and MRI revealed the deposition of iron in the liver, pancreas, and spleen, leading to the diagnosis of hemochromatosis. The concentration of interleukin-6 in serum was elevated. We speculate that the elevated serum interleukin-6 was associated with the etiology of the severe anemia and hemochromatosis in this patient.

Original languageEnglish
Pages (from-to)106-109
Number of pages4
JournalNishinihon Journal of Dermatology
Volume81
Issue number2
DOIs
Publication statusPublished - Jan 1 2019

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Hemochromatosis
Interleukin-6
Anemia
Serum
Subcutaneous Tissue
Dermis
Rectal Neoplasms
Blood Transfusion
Uterine Cervical Neoplasms
Pancreas
Ultrasonography
Spleen
Iron
Staining and Labeling
Skin
Liver
Therapeutics

All Science Journal Classification (ASJC) codes

  • Dermatology

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A case of secondary hemochromatosis with elevated serum interleukin-6. / Tsutsumi, Midori; Nakamura, Misa; Kawazu, Sotaro; Ito, Takamichi; Furue, Masutaka.

In: Nishinihon Journal of Dermatology, Vol. 81, No. 2, 01.01.2019, p. 106-109.

Research output: Contribution to journalArticle

Tsutsumi, Midori ; Nakamura, Misa ; Kawazu, Sotaro ; Ito, Takamichi ; Furue, Masutaka. / A case of secondary hemochromatosis with elevated serum interleukin-6. In: Nishinihon Journal of Dermatology. 2019 ; Vol. 81, No. 2. pp. 106-109.
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