A case of surgical resection for liver metastasis of gastric cancer with portal vein tumor thrombus

Tomoki Hata, Hiroshi Wada, Yoshito Tomimaru, Akira Tomokuni, Naoki Hama, Koichi Kawamoto, Shogo Kobayashi, Tadafumi Asaoka, Shigeru Marubashi, Hidetoshi Eguchi, Koji Umeshita, Shuji Takiguchi, Masaki Mori, Yuichiro Doki, Hiroaki Nagano

Research output: Contribution to journalArticle

Abstract

A 58-year-old man presented with anorexia and weight loss in April 2010. Endoscopic examination revealed a type 3 tumor extending from the gastric cardia to the antrum. Preoperative imaging showed liver metastasis (S8; 2 cm) and direct invasion of the cancer into the pancreas. We administered 4 courses of chemotherapy (DCS) for the unresectable tumor; the impact of the therapy was partial response (PR). We performed total gastrectomy, D2 dissection, splenectomy, distal pancreatectomy, and partial hepatectomy (S8) in April 2011. The patient was treated with 8 courses of adjuvant chemotherapy with S-1. In April 2012, abdominal computed tomography (CT) revealed a solitary recurrent lesion in the liver (S2). After 7 courses of chemotherapy(weekly paclitaxel), abdominal CT and magnetic resonance imaging (MRI) revealed a tumor thrombus in the portal vein extending from P2 to the umbilical portion (UP). We performed left hepatectomy and cholecystectomy due to the absence of new lesions. Histopathological findings revealed that the poorly differentiated adenocarcinoma had metastasized to the liver. Abdominal CT revealed the presence of multiple recurrent metastases in the liver, 4 months after the surgery. The patient died 27 months after the initial surgery and 7 months after the last operation.

Original languageEnglish
Pages (from-to)2136-2138
Number of pages3
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume41
Issue number12
Publication statusPublished - Nov 1 2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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  • Cite this

    Hata, T., Wada, H., Tomimaru, Y., Tomokuni, A., Hama, N., Kawamoto, K., Kobayashi, S., Asaoka, T., Marubashi, S., Eguchi, H., Umeshita, K., Takiguchi, S., Mori, M., Doki, Y., & Nagano, H. (2014). A case of surgical resection for liver metastasis of gastric cancer with portal vein tumor thrombus. Gan to kagaku ryoho. Cancer & chemotherapy, 41(12), 2136-2138.