A case of unresectable hilar bile duct cancer responding to chemo-radiotherapy by gemcitabine

Naohiko Kohya, Kazuyoshi Hashiguchi, Tomomi Yakabe, Atsushi Miyoshi, Takao Ohtsuka, Kenji Kitahara, Kohji Miyazaki

Research output: Contribution to journalArticle

Abstract

A 66-year-old woman was admitted to our hospital because of general fatigue and icterus. PTC findings showed irregular stenosis of hilar bile duct. Abdominal CT scan showed a dilatation of the intra-hepatic bile duct and a tumor around hilar bile duct. We diagnosed it as hilar bile duct carcinoma, and although we operated it was unresectable because of the metastasis of a para-aorta lymph node and duodenal invasion. We started chemo-radiotherapy with a total dose of 45 Gy and gemcitabine. The tumor and para-aorta lymph node were remarkably decreased, and tumor marker CA19-9 was also decreased to within the normal range. The patient had a peritoneal dissemination 10 months after the chemo-radiotherapy and survived 20 months.

Original languageEnglish
Pages (from-to)1753-1755
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Volume36
Issue number10
Publication statusPublished - Oct 2009
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Kohya, N., Hashiguchi, K., Yakabe, T., Miyoshi, A., Ohtsuka, T., Kitahara, K., & Miyazaki, K. (2009). A case of unresectable hilar bile duct cancer responding to chemo-radiotherapy by gemcitabine. Japanese Journal of Cancer and Chemotherapy, 36(10), 1753-1755.