A case successfully treated with subtotal esophagectomy after preoperative second-line chemotherapy for cT4 esophageal cancer

Takuya Honboh, Kensuke Kudo, Mizuki Ninomiya, Takayuki Hamatsu, Hirofumi Hasegawa, Akira Kabashima, Chie Ushijima, Masayuki Kitamura

Research output: Contribution to journalArticlepeer-review

Abstract

A 69-year-old male was diagnosed with type 2 advanced esophageal cancer in the upper and middle thoracic esophagus which invaded the left main bronchus and the aorta. Radio-chemotherapy was administered since a radical resection could not be performed due to the invasion. Two courses of enforced FP combination therapy (5-FU and CDDP) were administered along with radiotherapy. Although this radio-chemotherapy was effective to some degree in tumor reduction, a radical resection still could not be performed due to the invasion of the left main bronchus and the aorta. Thus, we administered four more courses of DCF combination therapy (docetaxel, CDDP and 5-FU). This chemotherapy reduced the esophageal cancer mass significantly, and subtotal esophagectomy was performed. No complications were observed after the operation. We conclude that DCF combination therapy may be effective in the treatment of esophageal cancer in cases which the desired effect cannot be achieved by FP combination therapy alone.

Original languageEnglish
Pages (from-to)2400-2402
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Volume37
Issue number12
Publication statusPublished - Nov 2010

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'A case successfully treated with subtotal esophagectomy after preoperative second-line chemotherapy for cT4 esophageal cancer'. Together they form a unique fingerprint.

Cite this