A clinicopathologic study of mucinous gastric carcinoma

Yosuke Adachi, Masaki Mori, Akinori Kido, Reishi Shimono, Yoshihiko Maehara, Keizo Sugimachi

Research output: Contribution to journalArticle

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Abstract

A clinicopathologic study of 42 mucinous gastric carcinomas (MGC) and 73 nonmucinous gastric carcinomas (NGC) was done. The tumor was defined as MGC when more than one half of tumor area had mucin pools. The 5‐year survival rate for curatively treated patients was almost the same in MGC (58%) and NGC (56%), and clinicopathologic features, except for lymphatic permeation, showed no significant difference between MGC and NGC. Findings in MGC patients who died of a recurrence within 3 years included total gastrectomy, upper location, large size, infiltrative growth, extraserosal invasion, positive lymph node metastasis, more advanced stage, and a noncurative operation. There was no significant correlation between the degree of mucin content and other data, including the prognosis. Histologically, MGC were divided into well‐differentiated and poorly differentiated types, according to the degree of glandular formation of the tumor cells. In patients with well‐differentiated MGC, the age of onset was older, tumor growth was localized, and there were metastases to the liver. In patients with poorly differentiated MGC, the age of onset was younger, tumor growth was infiltrative, and there was peritoneal dissemination. These results show that the biologic behavior of MGC is similar to that of NGC and that the lesion basically is determined by the histologic subtype, not by the mucin content. Cancer 1992; 69:866–871.

Original languageEnglish
Pages (from-to)866-871
Number of pages6
JournalCancer
Volume69
Issue number4
DOIs
Publication statusPublished - Feb 15 1992

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Mucinous Adenocarcinoma
Stomach
Mucins
Carcinoma
Neoplasms
Age of Onset
Growth
Neoplasm Metastasis
Gastrectomy

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

A clinicopathologic study of mucinous gastric carcinoma. / Adachi, Yosuke; Mori, Masaki; Kido, Akinori; Shimono, Reishi; Maehara, Yoshihiko; Sugimachi, Keizo.

In: Cancer, Vol. 69, No. 4, 15.02.1992, p. 866-871.

Research output: Contribution to journalArticle

Adachi, Yosuke ; Mori, Masaki ; Kido, Akinori ; Shimono, Reishi ; Maehara, Yoshihiko ; Sugimachi, Keizo. / A clinicopathologic study of mucinous gastric carcinoma. In: Cancer. 1992 ; Vol. 69, No. 4. pp. 866-871.
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