A computational method for determination of the mass-transfer coefficient in packed-bed immobilized enzyme reactors

Fumihide Shiraishi, Hiromitsu Miyakawa, Takahiro Hasegawa, Shino Kasai

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A computational method was developed that determined the mass-transfer coefficient k(L) or the volumetric mass-transfer coefficient k(L) a in packed-bed immobilized enzyme (IME) reactors. To study the performance of this method, two experimental systems were considered where an enzyme was immobilized on a non-porous support surface (surface-IME system) or within a porous support (pore-IME system). The values of k(L) and k(L) a determined in these packed-bed IME reactor systems were successfully expressed in terms of the substrate concentration at the reactor inlet and the liquid flow rate. Furthermore, the correlations obtained for k(L) and k(L) a were used to calculate the unconverted fractions of substrate at the reactor outlet. Comparison showed that the calculated results were in satisfactory agreement with the experimental values.

Original languageEnglish
Pages (from-to)405-413
Number of pages9
JournalJournal of Chemical Technology and Biotechnology
Volume66
Issue number4
DOIs
Publication statusPublished - Aug 1996
Externally publishedYes

Fingerprint

Immobilized Enzymes
Packed beds
Computational methods
mass transfer
Mass transfer
Enzymes
enzyme
Catalyst supports
Substrates
substrate
Flow rate
reactor
method
Liquids
liquid

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Chemical Engineering(all)
  • Renewable Energy, Sustainability and the Environment
  • Fuel Technology
  • Waste Management and Disposal
  • Pollution
  • Organic Chemistry
  • Inorganic Chemistry

Cite this

A computational method for determination of the mass-transfer coefficient in packed-bed immobilized enzyme reactors. / Shiraishi, Fumihide; Miyakawa, Hiromitsu; Hasegawa, Takahiro; Kasai, Shino.

In: Journal of Chemical Technology and Biotechnology, Vol. 66, No. 4, 08.1996, p. 405-413.

Research output: Contribution to journalArticle

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