A Cross-sectional comparison of the prevalence of obstructive sleep apnea symptoms in adults with down syndrome in Scotland and Japan

Elizabeth A. Hil, Hiroyuki Sawatari, Mari K. Nishizak, Donna M. Fairle, Akiko Chishaki, Kouta Funakoshi, Renata L. Rih, Shin Ichi Ando

Research output: Contribution to journalArticlepeer-review

Abstract

Small studies in Western populations report a high prevalence of obstructive sleep apnea (OSA) in adults with Down syndrome. To date, ethnic differences have not been explored. A questionnaire sent to 2,752 adults with Down syndrome aged 16 years in Scotland and Japan (789 valid responses) estimated OSA prevalence based on reported symptoms. Symptoms were common in both countries, with snoring (p=0.001) and arousals (p=0.04) more prevalent in Japan. Estimated OSA prevalence in adults with Down syndrome was similar in the two countries, and raised in comparison with the general adult population (19.6% in Scotland and 14.3% in Japan; p = 0.08), though BMI was a confounder. Identification and treatment of OSA is recommended in adults with Down syndrome, regardless of ethnicity.

Original languageEnglish
Pages (from-to)260-273
Number of pages14
JournalAmerican Journal on Intellectual and Developmental Disabilities
Volume125
Issue number4
DOIs
Publication statusPublished - Jul 1 2020

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Neuropsychology and Physiological Psychology
  • Developmental and Educational Psychology
  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Psychiatry and Mental health

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