TY - JOUR
T1 - A Cross-sectional comparison of the prevalence of obstructive sleep apnea symptoms in adults with down syndrome in Scotland and Japan
AU - Hil, Elizabeth A.
AU - Sawatari, Hiroyuki
AU - Nishizak, Mari K.
AU - Fairle, Donna M.
AU - Chishaki, Akiko
AU - Funakoshi, Kouta
AU - Rih, Renata L.
AU - Ando, Shin Ichi
N1 - Funding Information:
This work was funded by the Chief Scientist Office, Scotland [CZH/4/549], Baily Thomas Charitable Trust [TRUST/RNA/AC/TM/2634-5178] and Grant-in-Aid from the Japan Society for the Promotion of Science [253957 and 15K08715]. Abstracts based on this work have previously been presented in poster form at the 5th World Congress on Sleep Medicine, Valencia, 2013 and 3rd ESRS/ERS Sleep and Breathing Conference, Barcelona, 2015.
Publisher Copyright:
© 2020 American Association on Mental Retardation. All rights reserved.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - Small studies in Western populations report a high prevalence of obstructive sleep apnea (OSA) in adults with Down syndrome. To date, ethnic differences have not been explored. A questionnaire sent to 2,752 adults with Down syndrome aged 16 years in Scotland and Japan (789 valid responses) estimated OSA prevalence based on reported symptoms. Symptoms were common in both countries, with snoring (p=0.001) and arousals (p=0.04) more prevalent in Japan. Estimated OSA prevalence in adults with Down syndrome was similar in the two countries, and raised in comparison with the general adult population (19.6% in Scotland and 14.3% in Japan; p = 0.08), though BMI was a confounder. Identification and treatment of OSA is recommended in adults with Down syndrome, regardless of ethnicity.
AB - Small studies in Western populations report a high prevalence of obstructive sleep apnea (OSA) in adults with Down syndrome. To date, ethnic differences have not been explored. A questionnaire sent to 2,752 adults with Down syndrome aged 16 years in Scotland and Japan (789 valid responses) estimated OSA prevalence based on reported symptoms. Symptoms were common in both countries, with snoring (p=0.001) and arousals (p=0.04) more prevalent in Japan. Estimated OSA prevalence in adults with Down syndrome was similar in the two countries, and raised in comparison with the general adult population (19.6% in Scotland and 14.3% in Japan; p = 0.08), though BMI was a confounder. Identification and treatment of OSA is recommended in adults with Down syndrome, regardless of ethnicity.
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U2 - 10.1352/1944-7558-125.4.260
DO - 10.1352/1944-7558-125.4.260
M3 - Article
C2 - 32609806
AN - SCOPUS:85087474342
VL - 125
SP - 260
EP - 273
JO - American Journal on Intellectual and Developmental Disabilities
JF - American Journal on Intellectual and Developmental Disabilities
SN - 1944-7515
IS - 4
ER -
