A docking modelling rationally predicts strong binding of bisphenol A to estrogen-related receptor γ

Takeru Nose, Yasuyuki Shimohigashi

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

A computer-aided docking study was carried out to quickly clarify the binding structure of the ligand-receptor complex between bisphenol A (BPA), a well-known endocrine disruptor, and estrogen-related receptor γ (ERRγ). The resulting complex indicated that BPA binds to the ligand-binding pocket of ERRγ without any disruptions of the activation conformation.

Original languageEnglish
Pages (from-to)290-296
Number of pages7
JournalProtein and Peptide Letters
Volume15
Issue number3
DOIs
Publication statusPublished - Mar 1 2008

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Biochemistry

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