A Facile Surface Functionalization Method for Polymers Using a Nonsolvent

Toyoaki Hirata; Hidenobu Taneda; Kazuya Nishio; Manabu Inutsuka; Norifumi L. Yamada; Fumiya Nemoto; Yasuhisa Minagawa; Hisao Matsuno; Keiji Tanaka

doi:10.1021/acsabm.0c00028

A Facile Surface Functionalization Method for Polymers Using a Nonsolvent

Toyoaki Hirata, Hidenobu Taneda, Kazuya Nishio, Manabu Inutsuka, Norifumi L. Yamada, Fumiya Nemoto, Yasuhisa Minagawa, Hisao Matsuno, Keiji Tanaka

Applied Fine Chemistry

Research output: Contribution to journal › Article

Abstract

Surface treatment of polymeric solids without impairing their bulk properties is a crucial functionalization strategy for the promotion of their wider application. We here propose a facile method using a nonsolvent which can subtly alter or swell the polymer surface to be modified. A thin film of poly(methyl methacrylate) (PMMA) was immersed in a methanol solution of poly(2-methoxyethyl acrylate) (PMEA). Electron spectroscopy for chemical analysis and neutron reflectometry revealed that a PMEA layer formed on the PMMA film with a diffused interface. The PMEA layer was very swollen in water and exhibited the ability to suppress serum protein adsorption and platelet adhesion on it. The functionalization technique using a nonsolvent was also applicable to the surface of other polymeric solids such as polyurethane.

Original language	English
Pages (from-to)	2170-2176
Number of pages	7
Journal	ACS Applied Bio Materials
Volume	3
Issue number	4
DOIs	https://doi.org/10.1021/acsabm.0c00028
Publication status	Published - Apr 20 2020

All Science Journal Classification (ASJC) codes

Biomaterials
Chemistry(all)
Biomedical Engineering
Biochemistry, medical

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10.1021/acsabm.0c00028

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Hirata, T., Taneda, H., Nishio, K., Inutsuka, M., Yamada, N. L., Nemoto, F., Minagawa, Y., Matsuno, H., & Tanaka, K. (2020). A Facile Surface Functionalization Method for Polymers Using a Nonsolvent. ACS Applied Bio Materials, 3(4), 2170-2176. https://doi.org/10.1021/acsabm.0c00028

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abstract = "Surface treatment of polymeric solids without impairing their bulk properties is a crucial functionalization strategy for the promotion of their wider application. We here propose a facile method using a nonsolvent which can subtly alter or swell the polymer surface to be modified. A thin film of poly(methyl methacrylate) (PMMA) was immersed in a methanol solution of poly(2-methoxyethyl acrylate) (PMEA). Electron spectroscopy for chemical analysis and neutron reflectometry revealed that a PMEA layer formed on the PMMA film with a diffused interface. The PMEA layer was very swollen in water and exhibited the ability to suppress serum protein adsorption and platelet adhesion on it. The functionalization technique using a nonsolvent was also applicable to the surface of other polymeric solids such as polyurethane.",

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AU - Yamada, Norifumi L.

AU - Nemoto, Fumiya

AU - Minagawa, Yasuhisa

AU - Matsuno, Hisao

AU - Tanaka, Keiji

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