Abstract
Surface treatment of polymeric solids without impairing their bulk properties is a crucial functionalization strategy for the promotion of their wider application. We here propose a facile method using a nonsolvent which can subtly alter or swell the polymer surface to be modified. A thin film of poly(methyl methacrylate) (PMMA) was immersed in a methanol solution of poly(2-methoxyethyl acrylate) (PMEA). Electron spectroscopy for chemical analysis and neutron reflectometry revealed that a PMEA layer formed on the PMMA film with a diffused interface. The PMEA layer was very swollen in water and exhibited the ability to suppress serum protein adsorption and platelet adhesion on it. The functionalization technique using a nonsolvent was also applicable to the surface of other polymeric solids such as polyurethane.
Original language | English |
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Pages (from-to) | 2170-2176 |
Number of pages | 7 |
Journal | ACS Applied Bio Materials |
Volume | 3 |
Issue number | 4 |
DOIs | |
Publication status | Published - Apr 20 2020 |
All Science Journal Classification (ASJC) codes
- Biomaterials
- Chemistry(all)
- Biomedical Engineering
- Biochemistry, medical