A fatal case of necrotizing fasciitis due to bacterial translocation of Klebsiella oxytoca

Hirotaka Oishi, Yoshihiko Kagawa, Shinji Mitsumizo, Yukihiro Tashiro, Genta Kobayashi, Kazuma Udo, Shigehisa Aoki, Megumi Takayanagi, Zenzo Nagasawa, Kazukuni Araki, Noriko Ohza, Yuichiro Eguchi, Mikio Nakashima

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

We report a 73-year-old man with hepatocellular cell carcinoma who had eruptions on and severe pain in the lower leg. Within several hours, the patient's skin lesions had progressed markedly. Magnetic resonance imaging findings were consistent with necrotizing fasciitis. Klebsiella oxytoca was isolated from cultures of biopsy samples taken from the leg. The resulting DNA fingerprint pattern revealed that the enteric bacterium was the same as that obtained from the biopsy samples taken from the leg. Furthermore, a dendrogram showed that genetic proximity between samples was extremely high. These results confirmed that translocation of Klebsiella oxytoca as an enteric pathogen caused the necrotizing fasciitis in this patient.

Original languageEnglish
Pages (from-to)62-65
Number of pages4
JournalJournal of Infection and Chemotherapy
Volume14
Issue number1
DOIs
Publication statusPublished - Feb 2008
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

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