A functional [NiFe]hydrogenase mimic that catalyzes electron and hydride transfer from H2

Seiji Ogo, Koji Ichikawa, Takahiro Kishima, Takahiro Matsumoto, Hidetaka Nakai, Katsuhiro Kusaka, Takashi Ohhara

    Research output: Contribution to journalArticlepeer-review

    186 Citations (Scopus)

    Abstract

    Chemists have long sought to mimic enzymatic hydrogen activation with structurally simpler compounds. Here, we report a functional [NiFe]-based model of [NiFe]hydrogenase enzymes. This complex heterolytically activates hydrogen to form a hydride complex that is capable of reducing substrates by either hydride ion or electron transfer. Structural investigations were performed by a range of techniques, including x-ray diffraction and neutron scattering, resulting in crystal structures and the finding that the hydrido ligand is predominantly associated with the Fe center. The ligand's hydridic character is manifested in its reactivity with strong acid to liberate H2.

    Original languageEnglish
    Pages (from-to)682-684
    Number of pages3
    JournalScience
    Volume339
    Issue number6120
    DOIs
    Publication statusPublished - Feb 8 2013

    All Science Journal Classification (ASJC) codes

    • General

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