We performed laparoscopic splenectomy in combination with cholecystectomy in a 16-year-old girl with hereditary spherocytosis and cholecystolithiasis. The levels of hemoglogin and serum total bilirubin returned to normal immediately after surgery. The laparoscopic procedure is less invasive than open cholecystectomy or splenectomy in terms of the changes in serum interleukin 6 levels after surgery. This approach can be used in the treatment of spherocytosis with cholecystolithiasis, and it offers both functional and cosmetic advantages.
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