A mathematical model of cleavage

Masakazu Akiyama, Atsushi Tero, Ryo Kobayashi

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

In the present paper, we propose a mathematical model of cleavage. Cleavage is a process during the early stages of development in which the fertile egg undergoes repeated division keeping the cluster size almost constant. During the cleavage process individual cells repeat cell division in an orderly manner to form a blastula, however, the mechanism which achieves such a coordination is still not very clear. In the present research, we took sea urchin as an example and focused on the diffusion of chemical substances from the animal and vegetal pole. By considering chemotactic motion of the centrosomes, we constructed a mathematical model that describes the processes in the early stages of cleavage.

Original languageEnglish
Pages (from-to)84-94
Number of pages11
JournalJournal of Theoretical Biology
Volume264
Issue number1
DOIs
Publication statusPublished - May 7 2010
Externally publishedYes

Fingerprint

Theoretical Models
mathematical models
Mathematical Model
Mathematical models
Blastula
centrosomes
Centrosome
Sea Urchins
Echinoidea
Cell Division
Ovum
cell division
Poles
Animals
Cells
Pole
Division
Research
animals
Motion

All Science Journal Classification (ASJC) codes

  • Statistics and Probability
  • Modelling and Simulation
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Agricultural and Biological Sciences(all)
  • Applied Mathematics

Cite this

A mathematical model of cleavage. / Akiyama, Masakazu; Tero, Atsushi; Kobayashi, Ryo.

In: Journal of Theoretical Biology, Vol. 264, No. 1, 07.05.2010, p. 84-94.

Research output: Contribution to journalArticle

Akiyama, Masakazu ; Tero, Atsushi ; Kobayashi, Ryo. / A mathematical model of cleavage. In: Journal of Theoretical Biology. 2010 ; Vol. 264, No. 1. pp. 84-94.
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