Serum specimens of two unrelated Japanese males had a new variant of the α2HS-glycoprotein phenotypes. They had unusual bands designated AHS 5. Family studies indicated that the new variant phenotypes were determined by a new allele, AHS*5, in combination with a common allele AHS*1 or AHS*2, and that the new allele had an autosomal codominant inheritance with other AHS alleles. The frequency of the new α2HS-glycoprotein allele, AHS*5, is 0.0005.
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