A new aliphatic ester of hydroxysalicylic acid from fermented Carica papaya L. preparation with a potential hair growth stimulating activity

Ahmed Ashour, Yhiya Amen, Toshinori Nakagawa, Yasuharu Niwa, Amira Mira, Koichiro Ohnuki, Shinki Murakami, Mitsuko Imao, Kuniyoshi Shimizu

Research output: Contribution to journalArticle

Abstract

An aliphatic ester of hydroxysalicylic acid (6), reported for the first time from a natural source in addition to five known compounds were isolated from the fermented Carica papaya L. preparation, a commercialized functional food. The known compounds were identified as 5-hydroxymethylfurfuraldehyde (1), trans-caffeic acid (2), butyl 4-hydroxybenzoate (butylparaben) (3), lycopene (4), benzyl isothiocyanate (5). Compounds 1 and 3 were reported for the first time from Papaya fruits through this study. The new compound showed a moderate antioxidant activity and a potent hair growth stimulating activity in vitro.

Original languageEnglish
Pages (from-to)1750-1755
Number of pages6
JournalNatural Product Research
Volume34
Issue number12
DOIs
Publication statusPublished - Jun 17 2020

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Plant Science
  • Organic Chemistry

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