A new approach to asymmetric synthesis of β-amino alcohols by means of α-chirally protected amino alkyllithiums

Takahiro Tomoyasu, Katsuhiko Tomooka, Takeshi Nakai

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

A new, general synthetic approach to enantiopure α-amino ketones and syn-β-amino alcohols is described which employs the doubly chiral N-protected α-amino alkyllithiums generated via Pearson's transmetalative protocol as the key synthetic intermediates.

Original languageEnglish
Pages (from-to)1147-1149
Number of pages3
JournalSynlett
Issue number10
DOIs
Publication statusPublished - Jan 1 1998
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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