A new entry in catalytic alkynylation of aldehydes and ketones: Dual activation of soft nucleophiles and hard electrophiles by an indium(III) catalyst

Ryo Takita; Yuhei Fukuta; Riichiro Tsuji; Takashi Ohshima; Masakatsu Shibasaki

doi:10.1021/ol050069h

A new entry in catalytic alkynylation of aldehydes and ketones: Dual activation of soft nucleophiles and hard electrophiles by an indium(III) catalyst

Ryo Takita, Yuhei Fukuta, Riichiro Tsuji, Takashi Ohshima, Masakatsu Shibasaki

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

(Chemical Equation Presented). A new entry in catalytic alkynylation of carbonyl compounds was developed in which dual activation of both soft nucleophiles (terminal alkynes) and hard electrophiles (aldehydes and ketones) is achieved using an indium(III) catalyst. Preliminary mechanistic studies using in situ IR and NMR spectroscopic analysis are also discussed.

Original language	English
Pages (from-to)	1363-1366
Number of pages	4
Journal	Organic Letters
Volume	7
Issue number	7
DOIs	https://doi.org/10.1021/ol050069h
Publication status	Published - Mar 31 2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Molecular Medicine

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10.1021/ol050069h

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abstract = "(Chemical Equation Presented). A new entry in catalytic alkynylation of carbonyl compounds was developed in which dual activation of both soft nucleophiles (terminal alkynes) and hard electrophiles (aldehydes and ketones) is achieved using an indium(III) catalyst. Preliminary mechanistic studies using in situ IR and NMR spectroscopic analysis are also discussed.",

author = "Ryo Takita and Yuhei Fukuta and Riichiro Tsuji and Takashi Ohshima and Masakatsu Shibasaki",

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T2 - Dual activation of soft nucleophiles and hard electrophiles by an indium(III) catalyst

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AU - Fukuta, Yuhei

AU - Tsuji, Riichiro

AU - Ohshima, Takashi

AU - Shibasaki, Masakatsu

PY - 2005/3/31

Y1 - 2005/3/31

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AB - (Chemical Equation Presented). A new entry in catalytic alkynylation of carbonyl compounds was developed in which dual activation of both soft nucleophiles (terminal alkynes) and hard electrophiles (aldehydes and ketones) is achieved using an indium(III) catalyst. Preliminary mechanistic studies using in situ IR and NMR spectroscopic analysis are also discussed.

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A new entry in catalytic alkynylation of aldehydes and ketones: Dual activation of soft nucleophiles and hard electrophiles by an indium(III) catalyst

Abstract

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