A new index of cell fatigue under reciprocative stress test

K. Kuroda, W. Fukui, M. Kaneko, S. Sakuma, F. Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We propose a new index for indicating the fatigue state of a cell under reciprocative stress test. By using an input signal of square wave for cell position control, we impart an extremely high shear stress to a cell. We conducted the fatigue test on red blood cells (RBCs), and the shape of each RBC is observed while reciprocated motion is given. The results show that the shape of cell tail is eventually changed from concave to convex. Based on the observed phenomenon, the tail curvature is proposed as a new index for cell fatigue state.

Original languageEnglish
Title of host publication17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PublisherChemical and Biological Microsystems Society
Pages371-373
Number of pages3
ISBN (Print)9781632666246
Publication statusPublished - 2013
Externally publishedYes
Event17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
Duration: Oct 27 2013Oct 31 2013

Publication series

Name17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Volume1

Other

Other17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
CountryGermany
CityFreiburg
Period10/27/1310/31/13

All Science Journal Classification (ASJC) codes

  • Bioengineering

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