A New Ligand for Europium(III) That Forms a Stable Fluorescent Complex in Aqueous Solution

Daikichi Horiguchi, Yoshiki Katayama, Kazumi Sasamoto, Hideyuki Terasawa, Naofumi Sato, M. Mochizuki, Yosuke Ohkura

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A new macrocyclic ligand for Eu3 +, 24,30-diphenyl-8,19-(l,21:4,6:10,12:15,17-tetraetheno-8,9,19,20-tetrahydro-7AT,18^r-dibenzo[A,^][l,4,7,10,13,16]hexaazacyclooctadecine)diacetic acid (1), was synthesized and its fluorescence characteristics were examined, particularly to compare with 4,7-bis(chlorosulfophenyl)-l,10-phenanthroline-2,9-dicarboxylic acid (BCPDA) that has proved to be useful as a label in time-resolved fluoroimmunoassays. The complex of macrocycle 1 with Eu3+ was found to have a higher fluorescence intensity as well as a longer fluorescence lifetime than that of BCPDA.

Original languageEnglish
Pages (from-to)3334-3337
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume40
Issue number12
DOIs
Publication statusPublished - Jan 1 1992
Externally publishedYes

Fingerprint

Europium
Fluorescence
Ligands
Fluoroimmunoassay
Dicarboxylic Acids
Phenanthrolines
Labels
Acids
4,7-bis(chlorosulfophenyl)-1,10-phenanthroline-2,9-dicarboxylic acid

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

Cite this

A New Ligand for Europium(III) That Forms a Stable Fluorescent Complex in Aqueous Solution. / Horiguchi, Daikichi; Katayama, Yoshiki; Sasamoto, Kazumi; Terasawa, Hideyuki; Sato, Naofumi; Mochizuki, M.; Ohkura, Yosuke.

In: Chemical and Pharmaceutical Bulletin, Vol. 40, No. 12, 01.01.1992, p. 3334-3337.

Research output: Contribution to journalArticle

Horiguchi, D, Katayama, Y, Sasamoto, K, Terasawa, H, Sato, N, Mochizuki, M & Ohkura, Y 1992, 'A New Ligand for Europium(III) That Forms a Stable Fluorescent Complex in Aqueous Solution', Chemical and Pharmaceutical Bulletin, vol. 40, no. 12, pp. 3334-3337. https://doi.org/10.1248/cpb.40.3334
Horiguchi, Daikichi ; Katayama, Yoshiki ; Sasamoto, Kazumi ; Terasawa, Hideyuki ; Sato, Naofumi ; Mochizuki, M. ; Ohkura, Yosuke. / A New Ligand for Europium(III) That Forms a Stable Fluorescent Complex in Aqueous Solution. In: Chemical and Pharmaceutical Bulletin. 1992 ; Vol. 40, No. 12. pp. 3334-3337.
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