A new stilbene with tyrosinase inhibitory activity from Chlorophora excelsa

Kuniyoshi Shimizu, Seiji Yasutake, Ryuichiro Kondo

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

A new stilbene, 4-[(2″E)-7″-hydroxy-3″,7″- dimethyloct-2″-enyl]-2′,3,4′,5-tetrahydroxy-trans-stilbene (1), and the known compound chlorophorin (2) were isolated from the heartwood of Chlorophora excelsa. Both 1 and 2 showed tyrosinase inhibitory activity with IC50 values of 96 and 1.3 μM, respectively.

Original languageEnglish
Pages (from-to)318-319
Number of pages2
JournalChemical and Pharmaceutical Bulletin
Volume51
Issue number3
DOIs
Publication statusPublished - Jan 1 2003

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Stilbenes
Monophenol Monooxygenase
Inhibitory Concentration 50
chlorophorin

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

Cite this

A new stilbene with tyrosinase inhibitory activity from Chlorophora excelsa. / Shimizu, Kuniyoshi; Yasutake, Seiji; Kondo, Ryuichiro.

In: Chemical and Pharmaceutical Bulletin, Vol. 51, No. 3, 01.01.2003, p. 318-319.

Research output: Contribution to journalArticle

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