A Novel Approach to α-Silylmethylene-β-lactams via Rh-catalyzed Silylcarbonylation of Propargylamine Derivatives

Isamu Matsuda, Jun Sakakibara, Hideo Nagashima

Research output: Contribution to journalArticle

85 Citations (Scopus)


α-Silylmethylene-β-lactams are successfully constructed by the one-pot coupling of a substituted propargylamine derivative, a triorganosilane, and CO with the catalysis of Rh4(CO)12 and DBU.

Original languageEnglish
Pages (from-to)7431-7434
Number of pages4
JournalTetrahedron Letters
Issue number50
Publication statusPublished - Dec 9 1991
Externally publishedYes


All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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