A novel gene carrier responding to intracellular signal protein kinase Cα

Riki Toita, Jeong Hun Kang, Yuhua Jiang, Takeshi Mori, Takuro Niidome, Yoshiki Ktayama

Research output: Contribution to conferencePaper

Abstract

Gene therapy has been expected as a medical approach to treat tumors, inheritable diseases and so on. For gene therapy, effective delivery of gene to the target tissue is vitally important. Previously, we have proposed a novel approach for gene therapy using a drug delivery system responding to cellular signal (D-RECS), especially to protein kinase C (PKC) α. PKCα plays an important role in the differentiation and proliferation of tumor cell. It was known that extraordinary activation of PKCα is seen in many cancers such as breast cancer, melanoma, liver cancer and so on. In this study, PKCα was used as a target protein kinase for D-RECS.

Original languageEnglish
Number of pages1
Publication statusPublished - Dec 1 2006
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
Duration: Sep 20 2006Sep 22 2006

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
CountryJapan
CityToyama
Period9/20/069/22/06

Fingerprint

Gene therapy
Genes
Proteins
Tumors
Liver
Chemical activation
Cells
Tissue

All Science Journal Classification (ASJC) codes

  • Engineering(all)

Cite this

Toita, R., Kang, J. H., Jiang, Y., Mori, T., Niidome, T., & Ktayama, Y. (2006). A novel gene carrier responding to intracellular signal protein kinase Cα. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.

A novel gene carrier responding to intracellular signal protein kinase Cα. / Toita, Riki; Kang, Jeong Hun; Jiang, Yuhua; Mori, Takeshi; Niidome, Takuro; Ktayama, Yoshiki.

2006. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.

Research output: Contribution to conferencePaper

Toita, R, Kang, JH, Jiang, Y, Mori, T, Niidome, T & Ktayama, Y 2006, 'A novel gene carrier responding to intracellular signal protein kinase Cα', Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan, 9/20/06 - 9/22/06.
Toita R, Kang JH, Jiang Y, Mori T, Niidome T, Ktayama Y. A novel gene carrier responding to intracellular signal protein kinase Cα. 2006. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.
Toita, Riki ; Kang, Jeong Hun ; Jiang, Yuhua ; Mori, Takeshi ; Niidome, Takuro ; Ktayama, Yoshiki. / A novel gene carrier responding to intracellular signal protein kinase Cα. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.1 p.
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