A novel gene carrier responding to intracellular signal protein kinase Cα

Riki Toita, Jeong Hun Kang, Yuhua Jiang, Takeshi Mori, Takuro Niidome, Yoshiki Ktayama

    Research output: Contribution to conferencePaperpeer-review

    Abstract

    Gene therapy has been expected as a medical approach to treat tumors, inheritable diseases and so on. For gene therapy, effective delivery of gene to the target tissue is vitally important. Previously, we have proposed a novel approach for gene therapy using a drug delivery system responding to cellular signal (D-RECS), especially to protein kinase C (PKC) α. PKCα plays an important role in the differentiation and proliferation of tumor cell. It was known that extraordinary activation of PKCα is seen in many cancers such as breast cancer, melanoma, liver cancer and so on. In this study, PKCα was used as a target protein kinase for D-RECS.

    Original languageEnglish
    Number of pages1
    Publication statusPublished - Dec 1 2006
    Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan
    Duration: Sep 20 2006Sep 22 2006

    Other

    Other55th Society of Polymer Science Japan Symposium on Macromolecules
    Country/TerritoryJapan
    CityToyama
    Period9/20/069/22/06

    All Science Journal Classification (ASJC) codes

    • Engineering(all)

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