Abstract
Gene therapy has been expected as a medical approach to treat tumors, inheritable diseases and so on. For gene therapy, effective delivery of gene to the target tissue is vitally important. Previously, we have proposed a novel approach for gene therapy using a drug delivery system responding to cellular signal (D-RECS), especially to protein kinase C (PKC) α. PKCα plays an important role in the differentiation and proliferation of tumor cell. It was known that extraordinary activation of PKCα is seen in many cancers such as breast cancer, melanoma, liver cancer and so on. In this study, PKCα was used as a target protein kinase for D-RECS.
| Original language | English |
|---|---|
| Number of pages | 1 |
| Publication status | Published - Dec 1 2006 |
| Event | 55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan Duration: Sep 20 2006 → Sep 22 2006 |
Other
| Other | 55th Society of Polymer Science Japan Symposium on Macromolecules |
|---|---|
| Country | Japan |
| City | Toyama |
| Period | 9/20/06 → 9/22/06 |
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All Science Journal Classification (ASJC) codes
- Engineering(all)
Cite this
A novel gene carrier responding to intracellular signal protein kinase Cα. / Toita, Riki; Kang, Jeong Hun; Jiang, Yuhua; Mori, Takeshi; Niidome, Takuro; Ktayama, Yoshiki.
2006. Paper presented at 55th Society of Polymer Science Japan Symposium on Macromolecules, Toyama, Japan.Research output: Contribution to conference › Paper
}
TY - CONF
T1 - A novel gene carrier responding to intracellular signal protein kinase Cα
AU - Toita, Riki
AU - Kang, Jeong Hun
AU - Jiang, Yuhua
AU - Mori, Takeshi
AU - Niidome, Takuro
AU - Ktayama, Yoshiki
PY - 2006/12/1
Y1 - 2006/12/1
N2 - Gene therapy has been expected as a medical approach to treat tumors, inheritable diseases and so on. For gene therapy, effective delivery of gene to the target tissue is vitally important. Previously, we have proposed a novel approach for gene therapy using a drug delivery system responding to cellular signal (D-RECS), especially to protein kinase C (PKC) α. PKCα plays an important role in the differentiation and proliferation of tumor cell. It was known that extraordinary activation of PKCα is seen in many cancers such as breast cancer, melanoma, liver cancer and so on. In this study, PKCα was used as a target protein kinase for D-RECS.
AB - Gene therapy has been expected as a medical approach to treat tumors, inheritable diseases and so on. For gene therapy, effective delivery of gene to the target tissue is vitally important. Previously, we have proposed a novel approach for gene therapy using a drug delivery system responding to cellular signal (D-RECS), especially to protein kinase C (PKC) α. PKCα plays an important role in the differentiation and proliferation of tumor cell. It was known that extraordinary activation of PKCα is seen in many cancers such as breast cancer, melanoma, liver cancer and so on. In this study, PKCα was used as a target protein kinase for D-RECS.
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M3 - Paper
AN - SCOPUS:33846162514
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