A patient with delayed posthypoxic demyelination

A case report of hyperbaric oxygen treatment

Shiro Miura, Yasumasa Ohyagi, Masaharu Ohno, Isao Inoue, Hirofumi Ochi, Hiroyuki Murai, Hirokazu Furuya, Takeshi Yamada, Jun-Ichi Kira

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 62-year-old man who developed akinetic mutism with delayed white matter demyelination after hypoxia was treated with hyperbaric oxygen (HBO). HBO in the subacute period markedly improved the patient's activity in daily life, cognitive function and organization on EEG. 1H-MRS showed a recovery of aerobic metabolism of the neurons. However, dementia and cerebral atrophy slowly progressed despite HBO treatment. Thus, HBO had a beneficial effect on the activity of depressed neurons but did not improve the prognosis.

Original languageEnglish
Pages (from-to)311-314
Number of pages4
JournalClinical Neurology and Neurosurgery
Volume104
Issue number4
DOIs
Publication statusPublished - Aug 10 2002

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Demyelinating Diseases
Oxygen
Akinetic Mutism
Neurons
Therapeutics
Cognition
Atrophy
Dementia
Electroencephalography

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Cite this

A patient with delayed posthypoxic demyelination : A case report of hyperbaric oxygen treatment. / Miura, Shiro; Ohyagi, Yasumasa; Ohno, Masaharu; Inoue, Isao; Ochi, Hirofumi; Murai, Hiroyuki; Furuya, Hirokazu; Yamada, Takeshi; Kira, Jun-Ichi.

In: Clinical Neurology and Neurosurgery, Vol. 104, No. 4, 10.08.2002, p. 311-314.

Research output: Contribution to journalArticle

Miura, Shiro ; Ohyagi, Yasumasa ; Ohno, Masaharu ; Inoue, Isao ; Ochi, Hirofumi ; Murai, Hiroyuki ; Furuya, Hirokazu ; Yamada, Takeshi ; Kira, Jun-Ichi. / A patient with delayed posthypoxic demyelination : A case report of hyperbaric oxygen treatment. In: Clinical Neurology and Neurosurgery. 2002 ; Vol. 104, No. 4. pp. 311-314.
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