A peptide motif recognizing a polymer stereoregularity

Takeshi Serizawa, Toshiki Sawada, Hisao Matsuno, Teruhiko Matsubara, Toshinori Sato

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

A combinatorial phage display method was applied to films composed of a stereoregular polymer of methacrylates. The phage clones with selective affinity for isotactic (it) poly(methyl methacrylate) (PMMA) were isolated. Greater amounts of the phage clones bound to it-PMMA, compared to other stereoregular PMMAs. The phage expressing ELWRPTR most strongly bound to the polymer, and the selectivity was also the best. The peptide motif essential for the specific interaction with the stereoregular polymer was revealed.

Original languageEnglish
Pages (from-to)13780-13781
Number of pages2
JournalJournal of the American Chemical Society
Volume127
Issue number40
DOIs
Publication statusPublished - Oct 12 2005
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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