A peptide motif recognizing a polymer stereoregularity

Takeshi Serizawa, Toshiki Sawada, Hisao Matsuno, Teruhiko Matsubara, Toshinori Sato

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

A combinatorial phage display method was applied to films composed of a stereoregular polymer of methacrylates. The phage clones with selective affinity for isotactic (it) poly(methyl methacrylate) (PMMA) were isolated. Greater amounts of the phage clones bound to it-PMMA, compared to other stereoregular PMMAs. The phage expressing ELWRPTR most strongly bound to the polymer, and the selectivity was also the best. The peptide motif essential for the specific interaction with the stereoregular polymer was revealed.

Original languageEnglish
Pages (from-to)13780-13781
Number of pages2
JournalJournal of the American Chemical Society
Volume127
Issue number40
DOIs
Publication statusPublished - Oct 12 2005
Externally publishedYes

Fingerprint

Bacteriophages
Peptides
Polymers
Polymethyl Methacrylate
Polymethyl methacrylates
Clone Cells
Methacrylates
Display devices

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

A peptide motif recognizing a polymer stereoregularity. / Serizawa, Takeshi; Sawada, Toshiki; Matsuno, Hisao; Matsubara, Teruhiko; Sato, Toshinori.

In: Journal of the American Chemical Society, Vol. 127, No. 40, 12.10.2005, p. 13780-13781.

Research output: Contribution to journalArticle

Serizawa, T, Sawada, T, Matsuno, H, Matsubara, T & Sato, T 2005, 'A peptide motif recognizing a polymer stereoregularity', Journal of the American Chemical Society, vol. 127, no. 40, pp. 13780-13781. https://doi.org/10.1021/ja054402o
Serizawa, Takeshi ; Sawada, Toshiki ; Matsuno, Hisao ; Matsubara, Teruhiko ; Sato, Toshinori. / A peptide motif recognizing a polymer stereoregularity. In: Journal of the American Chemical Society. 2005 ; Vol. 127, No. 40. pp. 13780-13781.
@article{1138cfcca0624e9b9a7880b975589edf,
title = "A peptide motif recognizing a polymer stereoregularity",
abstract = "A combinatorial phage display method was applied to films composed of a stereoregular polymer of methacrylates. The phage clones with selective affinity for isotactic (it) poly(methyl methacrylate) (PMMA) were isolated. Greater amounts of the phage clones bound to it-PMMA, compared to other stereoregular PMMAs. The phage expressing ELWRPTR most strongly bound to the polymer, and the selectivity was also the best. The peptide motif essential for the specific interaction with the stereoregular polymer was revealed.",
author = "Takeshi Serizawa and Toshiki Sawada and Hisao Matsuno and Teruhiko Matsubara and Toshinori Sato",
year = "2005",
month = "10",
day = "12",
doi = "10.1021/ja054402o",
language = "English",
volume = "127",
pages = "13780--13781",
journal = "Journal of the American Chemical Society",
issn = "0002-7863",
publisher = "American Chemical Society",
number = "40",

}

TY - JOUR

T1 - A peptide motif recognizing a polymer stereoregularity

AU - Serizawa, Takeshi

AU - Sawada, Toshiki

AU - Matsuno, Hisao

AU - Matsubara, Teruhiko

AU - Sato, Toshinori

PY - 2005/10/12

Y1 - 2005/10/12

N2 - A combinatorial phage display method was applied to films composed of a stereoregular polymer of methacrylates. The phage clones with selective affinity for isotactic (it) poly(methyl methacrylate) (PMMA) were isolated. Greater amounts of the phage clones bound to it-PMMA, compared to other stereoregular PMMAs. The phage expressing ELWRPTR most strongly bound to the polymer, and the selectivity was also the best. The peptide motif essential for the specific interaction with the stereoregular polymer was revealed.

AB - A combinatorial phage display method was applied to films composed of a stereoregular polymer of methacrylates. The phage clones with selective affinity for isotactic (it) poly(methyl methacrylate) (PMMA) were isolated. Greater amounts of the phage clones bound to it-PMMA, compared to other stereoregular PMMAs. The phage expressing ELWRPTR most strongly bound to the polymer, and the selectivity was also the best. The peptide motif essential for the specific interaction with the stereoregular polymer was revealed.

UR - http://www.scopus.com/inward/record.url?scp=26444514933&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=26444514933&partnerID=8YFLogxK

U2 - 10.1021/ja054402o

DO - 10.1021/ja054402o

M3 - Article

VL - 127

SP - 13780

EP - 13781

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

SN - 0002-7863

IS - 40

ER -