TY - JOUR
T1 - A pilot study of a simple screening technique for estimation of salivary flow
AU - Kanehira, Takashi
AU - Yamaguchi, Tomotaka
AU - Takehara, Junji
AU - Kashiwazaki, Haruhiko
AU - Abe, Takae
AU - Morita, Manabu
AU - Asano, Kouzo
AU - Fujii, Yoshinori
AU - Sakamoto, Wataru
PY - 2009/9
Y1 - 2009/9
N2 - Objectives: The purpose of this study was to develop a simple screening technique for estimation of salivary flow and to test the usefulness of the method for determining decreased salivary flow. Study design: A novel assay system comprising 3 spots containing 30 μg starch and 49.6 μg potassium iodide per spot on filter paper and a coloring reagent, based on the color reaction of iodine-starch and theory of paper chromatography, was designed. We investigated the relationship between resting whole salivary rates and the number of colored spots on the filter produced by 41 hospitalized subjects. Results: A significant negative correlation was observed between the number of colored spots and the resting salivary flow rate (n = 41; r = -0.803; P < .01). For all complaints of decreased salivary flow (n = 9) having cutoff values <100 μL/min for the salivary flow rate, 3 colored spots appeared on the paper, whereas for healthy subjects there was ≤1 colored spot. Conclusion: This novel assay system might be effective for estimation of salivary flow not only in healthy but also in bedridden and disabled elderly people.
AB - Objectives: The purpose of this study was to develop a simple screening technique for estimation of salivary flow and to test the usefulness of the method for determining decreased salivary flow. Study design: A novel assay system comprising 3 spots containing 30 μg starch and 49.6 μg potassium iodide per spot on filter paper and a coloring reagent, based on the color reaction of iodine-starch and theory of paper chromatography, was designed. We investigated the relationship between resting whole salivary rates and the number of colored spots on the filter produced by 41 hospitalized subjects. Results: A significant negative correlation was observed between the number of colored spots and the resting salivary flow rate (n = 41; r = -0.803; P < .01). For all complaints of decreased salivary flow (n = 9) having cutoff values <100 μL/min for the salivary flow rate, 3 colored spots appeared on the paper, whereas for healthy subjects there was ≤1 colored spot. Conclusion: This novel assay system might be effective for estimation of salivary flow not only in healthy but also in bedridden and disabled elderly people.
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U2 - 10.1016/j.tripleo.2009.04.019
DO - 10.1016/j.tripleo.2009.04.019
M3 - Article
C2 - 19577492
AN - SCOPUS:69049094839
SN - 2212-4403
VL - 108
SP - 389
EP - 393
JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
IS - 3
ER -