TY - JOUR
T1 - A porphyrin tetramer for a positive homotropic allosteric recognition system
T2 - Efficient binding information transduction through butadiynyl axis rotation
AU - Kubo, Yohei
AU - Ikeda, Masato
AU - Sugasaki, Atsushi
AU - Takeuchi, Masayuki
AU - Shinkai, Seiji
PY - 2001/10/15
Y1 - 2001/10/15
N2 - A porphyrin tetramer 1 was newly designed and synthesized to construct a novel allosteric guest-binding system. Compound 1 has a butadiynyl rotational axis, which is expected to act as a guest-binding information transducer. In chloroform, 1 can bind bidentate amines, such as 1,3-di(4-piperidyl)propane (DPP), in an allosteric manner to produce a 1:2 1/diamine complex with a Hill coefficient of 1.9.
AB - A porphyrin tetramer 1 was newly designed and synthesized to construct a novel allosteric guest-binding system. Compound 1 has a butadiynyl rotational axis, which is expected to act as a guest-binding information transducer. In chloroform, 1 can bind bidentate amines, such as 1,3-di(4-piperidyl)propane (DPP), in an allosteric manner to produce a 1:2 1/diamine complex with a Hill coefficient of 1.9.
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U2 - 10.1016/S0040-4039(01)01546-5
DO - 10.1016/S0040-4039(01)01546-5
M3 - Article
AN - SCOPUS:0035888227
SN - 0040-4039
VL - 42
SP - 7435
EP - 7438
JO - Tetrahedron Letters
JF - Tetrahedron Letters
IS - 42
ER -