A practical one-pot synthesis of 2,3-disubstituted indoles from unactivated anilines

Makoto Tokunaga, Mitsuru Ota, Masa aki Haga, Yasuo Wakatsuki

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

2-Substituted-3-methyl indoles are synthesized with good regioselectivity from readily available substrates and catalysts, i.e. the reaction of anilines with propargyl alcohols in the presence of 0.36-1 mol% Ru3(CO)12.

Original languageEnglish
Pages (from-to)3865-3868
Number of pages4
JournalTetrahedron Letters
Volume42
Issue number23
DOIs
Publication statusPublished - Jun 4 2001
Externally publishedYes

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Aniline Compounds
Indoles
Regioselectivity
Carbon Monoxide
Catalysts
Substrates
propargyl alcohol

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

A practical one-pot synthesis of 2,3-disubstituted indoles from unactivated anilines. / Tokunaga, Makoto; Ota, Mitsuru; Haga, Masa aki; Wakatsuki, Yasuo.

In: Tetrahedron Letters, Vol. 42, No. 23, 04.06.2001, p. 3865-3868.

Research output: Contribution to journalArticle

Tokunaga, Makoto ; Ota, Mitsuru ; Haga, Masa aki ; Wakatsuki, Yasuo. / A practical one-pot synthesis of 2,3-disubstituted indoles from unactivated anilines. In: Tetrahedron Letters. 2001 ; Vol. 42, No. 23. pp. 3865-3868.
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