A practical survey of liver cirrhosis and hepatocellular carcinoma in national kyushu cancer center hospital

Eighty-seven cases of liver cirrhosis (LC) and 138 cases of hepatocellular carcinoma (HCC) were admitted to National Kyushu Cancer Center Hospital from 1983 to 1987. We reviewed the etiological data, result of the therapy and prognosis of these patients. 1) HBsAg was positive in 14.9% of the patients with LC, and 20.7% of the patients were alcoholic. 35.6% of the patients had esophageal varices and 21.8% of the patients had gall stones. Five years survival rate of the LC patients was 54.3%. Most frequent cause of death was HCC. The cases whose serum was positive (>20 ng/ml) for alfa-feto-protein (AFP) progressed more frequently to HCC compared with AFP negative patients. 2) HBsAg was positive in 21% of the patients with HCC, and 30.4% of the patients were alcoholic. 11.6% of the patients had a history of blood transfusion. 59.4% of the patients were treated by transcatheter arterial embolization. One year survival rate of stages II and III patients was 75.5% and that of stage IV patients was 34.1%. Two-year-survival rate of the stages II and III patients was 47.1% and that of stage IV patients was 21.4%. Three-year-survival rate of stages II and III patients was 23.8%.