A practical synthetic method for enantio-enriched α-hydroxystannanes

Katsuhiko Tomooka, Tatsuya Igarashi, Takeshi Nakai

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The TiCl4-promoted reaction of (4S, 6S)-(4,6-dimethyl-1,3-dioxan-2-yl)tributylstannane with Grignard reagents is shown to afford, after oxidation followed by base treatment, the (S)-α-hydroxystannanes in >95∼20% ee.

Original languageEnglish
Pages (from-to)1913-1916
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number12
DOIs
Publication statusPublished - Mar 21 1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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