A pregnant woman with complications of lymphangioleiomyomatosis and idiopathic thrombocytopenic purpura

Kazuhiro Toyoda, Koichiro Matsumoto, Hiromasa Inoue, Masashi Komori, Masaki Fujita, Shuichi Hashimoto, Kazuyoshi Kuwano, Yoichi Nakanishi

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

A pregnant 26-year-old woman developed hemosputum, dyspnea and pneumothorax. Lymphangioleiomyomatosis was suspected based on multiple cystic lesions on chest computed tomography. Additionally, moderate thrombocytopenia occurred during the last trimester. Hyperplasia of megakaryocytes in a bone marrow specimen and a high serum titer of platelet-associated IgG led to a diagnosis of idiopathic thrombocytopenic purpura. High-dose intravenous gammaglobulin promptly restored her platelet count, and the patient successfully gave birth to a healthy baby by cesarean section. After delivery, lymphangioleiomyomatosis was diagnosed by lung biopsy that was obtained during a video-assisted thoracoscopic abscission for recurrent pneurnothorax. Underlying lymphangioleiomyomatosis and idiopathic thrombocytopenic purpura may be obviated by pregnancy.

Original languageEnglish
Pages (from-to)1097-1100
Number of pages4
JournalInternal Medicine
Volume45
Issue number19
DOIs
Publication statusPublished - Nov 1 2006

All Science Journal Classification (ASJC) codes

  • Internal Medicine

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