Abstract
Objective Streptococcus pneumoniae is an important and common pathogen of acute pneumonia. The urinary pneumococcal antigen test has been increasingly used for the diagnosis of pneumococcal pneumonia, but there have been few studies on pneumococcal pneumonia after this test became prevalent. The present study was conducted to characterize the clinical features of pneumococcal pneumonia after the introduction of the urinary antigen test. Methods We retrospectively analyzed 111 cases from 105 patients with pneumococcal pneumonia in our hospital between 2007 and 2010, and collected data regarding background characteristics, laboratory data, isolated bacteria, and clinical courses. Results The cases analysed included 77 of community-acquired pneumonia (CAP), 21 of healthcareassociated pneumonia (HCAP), and 13 of hospital-acquired pneumonia (HAP). Penicillin-resistant Streptococcus pneumoniae was isolated in 12.5 and 55.6% of non-HAP and HAP cases, respectively. When the cases were divided into 5 groups according to A-DROP scores (0, 1, 2, 3 and 4 points), critical events occurred at 0, 0, 8.7, 15.4, and 75.0% in groups of cases of 0, 1, 2, 3, and 4 points, respectively. Similarly, critical events occurred at 66.7, 4.7, 3.8, and 9.1% in groups of cases according to WBC counts of <4,000, 4,000-9,999, 10,000-19,999, and ≥20,000 cells/μL, respectively. Conclusion Most of the pneumococcal pneumonia cases occurred as CAP and were treated successfully. HAP cases were frequently penicillin resistant. Elevated A-DROP scores and decreased WBC counts were found to be predictive of critical events.
| Original language | English |
|---|---|
| Pages (from-to) | 37-43 |
| Number of pages | 7 |
| Journal | Internal Medicine |
| Volume | 51 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 4 2012 |
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All Science Journal Classification (ASJC) codes
- Internal Medicine
Cite this
A retrospective analysis of 111 cases of pneumococcal pneumonia : Clinical features and prognostic factors. / Ikegame, Satoshi; Wakamatsu, Kentaro; Kumazoe, Hiroyuki; Kawasaki, Masayuki; Fujita, Masaki; Nakanishi, Yoichi; Harada, Mine; Kajiki, Akira.
In: Internal Medicine, Vol. 51, No. 1, 04.01.2012, p. 37-43.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A retrospective analysis of 111 cases of pneumococcal pneumonia
T2 - Clinical features and prognostic factors
AU - Ikegame, Satoshi
AU - Wakamatsu, Kentaro
AU - Kumazoe, Hiroyuki
AU - Kawasaki, Masayuki
AU - Fujita, Masaki
AU - Nakanishi, Yoichi
AU - Harada, Mine
AU - Kajiki, Akira
PY - 2012/1/4
Y1 - 2012/1/4
N2 - Objective Streptococcus pneumoniae is an important and common pathogen of acute pneumonia. The urinary pneumococcal antigen test has been increasingly used for the diagnosis of pneumococcal pneumonia, but there have been few studies on pneumococcal pneumonia after this test became prevalent. The present study was conducted to characterize the clinical features of pneumococcal pneumonia after the introduction of the urinary antigen test. Methods We retrospectively analyzed 111 cases from 105 patients with pneumococcal pneumonia in our hospital between 2007 and 2010, and collected data regarding background characteristics, laboratory data, isolated bacteria, and clinical courses. Results The cases analysed included 77 of community-acquired pneumonia (CAP), 21 of healthcareassociated pneumonia (HCAP), and 13 of hospital-acquired pneumonia (HAP). Penicillin-resistant Streptococcus pneumoniae was isolated in 12.5 and 55.6% of non-HAP and HAP cases, respectively. When the cases were divided into 5 groups according to A-DROP scores (0, 1, 2, 3 and 4 points), critical events occurred at 0, 0, 8.7, 15.4, and 75.0% in groups of cases of 0, 1, 2, 3, and 4 points, respectively. Similarly, critical events occurred at 66.7, 4.7, 3.8, and 9.1% in groups of cases according to WBC counts of <4,000, 4,000-9,999, 10,000-19,999, and ≥20,000 cells/μL, respectively. Conclusion Most of the pneumococcal pneumonia cases occurred as CAP and were treated successfully. HAP cases were frequently penicillin resistant. Elevated A-DROP scores and decreased WBC counts were found to be predictive of critical events.
AB - Objective Streptococcus pneumoniae is an important and common pathogen of acute pneumonia. The urinary pneumococcal antigen test has been increasingly used for the diagnosis of pneumococcal pneumonia, but there have been few studies on pneumococcal pneumonia after this test became prevalent. The present study was conducted to characterize the clinical features of pneumococcal pneumonia after the introduction of the urinary antigen test. Methods We retrospectively analyzed 111 cases from 105 patients with pneumococcal pneumonia in our hospital between 2007 and 2010, and collected data regarding background characteristics, laboratory data, isolated bacteria, and clinical courses. Results The cases analysed included 77 of community-acquired pneumonia (CAP), 21 of healthcareassociated pneumonia (HCAP), and 13 of hospital-acquired pneumonia (HAP). Penicillin-resistant Streptococcus pneumoniae was isolated in 12.5 and 55.6% of non-HAP and HAP cases, respectively. When the cases were divided into 5 groups according to A-DROP scores (0, 1, 2, 3 and 4 points), critical events occurred at 0, 0, 8.7, 15.4, and 75.0% in groups of cases of 0, 1, 2, 3, and 4 points, respectively. Similarly, critical events occurred at 66.7, 4.7, 3.8, and 9.1% in groups of cases according to WBC counts of <4,000, 4,000-9,999, 10,000-19,999, and ≥20,000 cells/μL, respectively. Conclusion Most of the pneumococcal pneumonia cases occurred as CAP and were treated successfully. HAP cases were frequently penicillin resistant. Elevated A-DROP scores and decreased WBC counts were found to be predictive of critical events.
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UR - http://www.scopus.com/inward/citedby.url?scp=84855244106&partnerID=8YFLogxK
U2 - 10.2169/internalmedicine.51.5847
DO - 10.2169/internalmedicine.51.5847
M3 - Article
C2 - 22214621
AN - SCOPUS:84855244106
VL - 51
SP - 37
EP - 43
JO - Internal Medicine
JF - Internal Medicine
SN - 0918-2918
IS - 1
ER -