TY - JOUR

T1 - A simple and accurate formula to estimate left hepatic graft volume in living-donor adult liver transplantation

AU - Harada, Noboru

AU - Shimada, Mitsuo

AU - Yoshizumi, Tomoharu

AU - Suehiro, Taketoshi

AU - Soejima, Yuji

AU - Maehara, Yoshihiko

PY - 2004/5/27

Y1 - 2004/5/27

N2 - Background. In the field of living-donor adult liver transplantation, a small-for-size graft often occurs, particularly when using left-lobe grafts. This is because of the limited volumes associated with left-lobe grafts. The accurate preoperative evaluation of graft volumes is crucial to avoid this complication. The aim of this study is to clarify the usefulness of a new formula to estimate the left-lobe graft volume. Method. In 61 left-lobe grafts, a new formula was created with stepwise regression analysis using the following variables: height, weight, the thoracic and abdominal distance from anterior to posterior side (A-P), and distance from left to right side (L-R) of the initial 20 donors. With another 41 donors, the difference between the actual and estimated graft volume using the formula and two-and three-dimensional computed tomography was prospectively evaluated. Results. On the basis of the results of the stepwise regression analysis, a new formula was created as follows: graft volume (ml)=313.4+7.7xweight (kg)-12.6xthoracic L-R (cm). The difference between the actual and estimated graft volumes using the formula was significantly better (10.8±9.5%) than that of the volumetry using two-dimensional computed tomography (16.3±10.1%) (P<0.05). Conclusions. In conclusion, the new formula can estimate the actual graft volume more accurately than conventional volumetry with two-dimensional computed tomography. The formula is useful to estimate the volume of left-lobe graft in living-donor adult liver transplantation.

AB - Background. In the field of living-donor adult liver transplantation, a small-for-size graft often occurs, particularly when using left-lobe grafts. This is because of the limited volumes associated with left-lobe grafts. The accurate preoperative evaluation of graft volumes is crucial to avoid this complication. The aim of this study is to clarify the usefulness of a new formula to estimate the left-lobe graft volume. Method. In 61 left-lobe grafts, a new formula was created with stepwise regression analysis using the following variables: height, weight, the thoracic and abdominal distance from anterior to posterior side (A-P), and distance from left to right side (L-R) of the initial 20 donors. With another 41 donors, the difference between the actual and estimated graft volume using the formula and two-and three-dimensional computed tomography was prospectively evaluated. Results. On the basis of the results of the stepwise regression analysis, a new formula was created as follows: graft volume (ml)=313.4+7.7xweight (kg)-12.6xthoracic L-R (cm). The difference between the actual and estimated graft volumes using the formula was significantly better (10.8±9.5%) than that of the volumetry using two-dimensional computed tomography (16.3±10.1%) (P<0.05). Conclusions. In conclusion, the new formula can estimate the actual graft volume more accurately than conventional volumetry with two-dimensional computed tomography. The formula is useful to estimate the volume of left-lobe graft in living-donor adult liver transplantation.

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U2 - 10.1097/01.TP.0000131991.10802.AA

DO - 10.1097/01.TP.0000131991.10802.AA

M3 - Article

C2 - 15239624

AN - SCOPUS:2542528461

SN - 0041-1337

VL - 77

SP - 1571

EP - 1575

JO - Transplantation

JF - Transplantation

IS - 10

ER -