A simple and accurate formula to estimate left hepatic graft volume in living-donor adult liver transplantation

Noboru Harada, Mitsuo Shimada, Tomoharu Yoshizumi, Taketoshi Suehiro, Yuji Soejima, Yoshihiko Maehara

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Background. In the field of living-donor adult liver transplantation, a small-for-size graft often occurs, particularly when using left-lobe grafts. This is because of the limited volumes associated with left-lobe grafts. The accurate preoperative evaluation of graft volumes is crucial to avoid this complication. The aim of this study is to clarify the usefulness of a new formula to estimate the left-lobe graft volume. Method. In 61 left-lobe grafts, a new formula was created with stepwise regression analysis using the following variables: height, weight, the thoracic and abdominal distance from anterior to posterior side (A-P), and distance from left to right side (L-R) of the initial 20 donors. With another 41 donors, the difference between the actual and estimated graft volume using the formula and two-and three-dimensional computed tomography was prospectively evaluated. Results. On the basis of the results of the stepwise regression analysis, a new formula was created as follows: graft volume (ml)=313.4+7.7xweight (kg)-12.6xthoracic L-R (cm). The difference between the actual and estimated graft volumes using the formula was significantly better (10.8±9.5%) than that of the volumetry using two-dimensional computed tomography (16.3±10.1%) (P<0.05). Conclusions. In conclusion, the new formula can estimate the actual graft volume more accurately than conventional volumetry with two-dimensional computed tomography. The formula is useful to estimate the volume of left-lobe graft in living-donor adult liver transplantation.

Original languageEnglish
Pages (from-to)1571-1575
Number of pages5
JournalTransplantation
Volume77
Issue number10
DOIs
Publication statusPublished - May 27 2004

Fingerprint

Living Donors
Liver Transplantation
Transplants
Liver
Tomography
Regression Analysis
Tissue Donors
Thorax
Weights and Measures

All Science Journal Classification (ASJC) codes

  • Transplantation

Cite this

A simple and accurate formula to estimate left hepatic graft volume in living-donor adult liver transplantation. / Harada, Noboru; Shimada, Mitsuo; Yoshizumi, Tomoharu; Suehiro, Taketoshi; Soejima, Yuji; Maehara, Yoshihiko.

In: Transplantation, Vol. 77, No. 10, 27.05.2004, p. 1571-1575.

Research output: Contribution to journalArticle

Harada, Noboru ; Shimada, Mitsuo ; Yoshizumi, Tomoharu ; Suehiro, Taketoshi ; Soejima, Yuji ; Maehara, Yoshihiko. / A simple and accurate formula to estimate left hepatic graft volume in living-donor adult liver transplantation. In: Transplantation. 2004 ; Vol. 77, No. 10. pp. 1571-1575.
@article{d02246fa16434786ac4006ff780b5ca5,
title = "A simple and accurate formula to estimate left hepatic graft volume in living-donor adult liver transplantation",
abstract = "Background. In the field of living-donor adult liver transplantation, a small-for-size graft often occurs, particularly when using left-lobe grafts. This is because of the limited volumes associated with left-lobe grafts. The accurate preoperative evaluation of graft volumes is crucial to avoid this complication. The aim of this study is to clarify the usefulness of a new formula to estimate the left-lobe graft volume. Method. In 61 left-lobe grafts, a new formula was created with stepwise regression analysis using the following variables: height, weight, the thoracic and abdominal distance from anterior to posterior side (A-P), and distance from left to right side (L-R) of the initial 20 donors. With another 41 donors, the difference between the actual and estimated graft volume using the formula and two-and three-dimensional computed tomography was prospectively evaluated. Results. On the basis of the results of the stepwise regression analysis, a new formula was created as follows: graft volume (ml)=313.4+7.7xweight (kg)-12.6xthoracic L-R (cm). The difference between the actual and estimated graft volumes using the formula was significantly better (10.8±9.5{\%}) than that of the volumetry using two-dimensional computed tomography (16.3±10.1{\%}) (P<0.05). Conclusions. In conclusion, the new formula can estimate the actual graft volume more accurately than conventional volumetry with two-dimensional computed tomography. The formula is useful to estimate the volume of left-lobe graft in living-donor adult liver transplantation.",
author = "Noboru Harada and Mitsuo Shimada and Tomoharu Yoshizumi and Taketoshi Suehiro and Yuji Soejima and Yoshihiko Maehara",
year = "2004",
month = "5",
day = "27",
doi = "10.1097/01.TP.0000131991.10802.AA",
language = "English",
volume = "77",
pages = "1571--1575",
journal = "Transplantation",
issn = "0041-1337",
publisher = "Lippincott Williams and Wilkins",
number = "10",

}

TY - JOUR

T1 - A simple and accurate formula to estimate left hepatic graft volume in living-donor adult liver transplantation

AU - Harada, Noboru

AU - Shimada, Mitsuo

AU - Yoshizumi, Tomoharu

AU - Suehiro, Taketoshi

AU - Soejima, Yuji

AU - Maehara, Yoshihiko

PY - 2004/5/27

Y1 - 2004/5/27

N2 - Background. In the field of living-donor adult liver transplantation, a small-for-size graft often occurs, particularly when using left-lobe grafts. This is because of the limited volumes associated with left-lobe grafts. The accurate preoperative evaluation of graft volumes is crucial to avoid this complication. The aim of this study is to clarify the usefulness of a new formula to estimate the left-lobe graft volume. Method. In 61 left-lobe grafts, a new formula was created with stepwise regression analysis using the following variables: height, weight, the thoracic and abdominal distance from anterior to posterior side (A-P), and distance from left to right side (L-R) of the initial 20 donors. With another 41 donors, the difference between the actual and estimated graft volume using the formula and two-and three-dimensional computed tomography was prospectively evaluated. Results. On the basis of the results of the stepwise regression analysis, a new formula was created as follows: graft volume (ml)=313.4+7.7xweight (kg)-12.6xthoracic L-R (cm). The difference between the actual and estimated graft volumes using the formula was significantly better (10.8±9.5%) than that of the volumetry using two-dimensional computed tomography (16.3±10.1%) (P<0.05). Conclusions. In conclusion, the new formula can estimate the actual graft volume more accurately than conventional volumetry with two-dimensional computed tomography. The formula is useful to estimate the volume of left-lobe graft in living-donor adult liver transplantation.

AB - Background. In the field of living-donor adult liver transplantation, a small-for-size graft often occurs, particularly when using left-lobe grafts. This is because of the limited volumes associated with left-lobe grafts. The accurate preoperative evaluation of graft volumes is crucial to avoid this complication. The aim of this study is to clarify the usefulness of a new formula to estimate the left-lobe graft volume. Method. In 61 left-lobe grafts, a new formula was created with stepwise regression analysis using the following variables: height, weight, the thoracic and abdominal distance from anterior to posterior side (A-P), and distance from left to right side (L-R) of the initial 20 donors. With another 41 donors, the difference between the actual and estimated graft volume using the formula and two-and three-dimensional computed tomography was prospectively evaluated. Results. On the basis of the results of the stepwise regression analysis, a new formula was created as follows: graft volume (ml)=313.4+7.7xweight (kg)-12.6xthoracic L-R (cm). The difference between the actual and estimated graft volumes using the formula was significantly better (10.8±9.5%) than that of the volumetry using two-dimensional computed tomography (16.3±10.1%) (P<0.05). Conclusions. In conclusion, the new formula can estimate the actual graft volume more accurately than conventional volumetry with two-dimensional computed tomography. The formula is useful to estimate the volume of left-lobe graft in living-donor adult liver transplantation.

UR - http://www.scopus.com/inward/record.url?scp=2542528461&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=2542528461&partnerID=8YFLogxK

U2 - 10.1097/01.TP.0000131991.10802.AA

DO - 10.1097/01.TP.0000131991.10802.AA

M3 - Article

C2 - 15239624

AN - SCOPUS:2542528461

VL - 77

SP - 1571

EP - 1575

JO - Transplantation

JF - Transplantation

SN - 0041-1337

IS - 10

ER -